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(infant carrier)
9,919 results
  • Carrying human infants - An evolutionary heritage. [Review]
    Infant Behav Dev. 2020 Jun 19; 60:101460.Berecz B, Cyrille M, … Norholt H
  • We propose that infant carrying is a biological norm for human caregiving, given that human infants have evolved a capacity to cling onto an upright caregiver whose body co-evolved to enable offspring carrying. The origins of this mutual adaptation may date back 4 million years, with the emergence of bipedalism, which precluded the infant horizontal and gravity-supported position on the back of a…
  • StatPearls: Genetics, X-Linked Inheritance [BOOK]
    . StatPearls Publishing: Treasure Island (FL) Basta Marina M St. George's University, School of Medicine Pandya Ashish M. AM Saurashtra University Rajkot India. PDU Goverment Medical College & Hospital Rajkot Gujarat India BOOK
  • The X chromosome contains 867 identified genes; most of these genes are responsible for the development of tissues like bone, neural, blood, hepatic, renal, retina, ears, ear, cardiac,  skin, and teeth. There are at least 533 disorders due to the involvement of the genes on the X chromosome.[1] A 'trait' or 'disorder' determined by a gene on the X  chromosome demonstrates X-linked inheritance.  I…
  • Implementation of population-based newborn screening reveals low incidence of spinal muscular atrophy. [Journal Article]
    Genet Med. 2020 May 18 [Online ahead of print]Kay DM, Stevens CF, … Caggana M
  • CONCLUSIONS: Newborn screening permits presymptomatic SMA diagnosis, when treatment initiation is most beneficial. At 1 in 28,137 (95% confidence interval [CI]: 1 in 14,259 to 55,525), the NYS SMA incidence is 2.6- to 4.7-fold lower than expected. The low SMA incidence is likely attributable to imprecise and biased estimates, coupled with increased awareness, access to and uptake of carrier screening, genetic counseling, cascade testing, prenatal diagnosis, and advanced reproductive technologies.
  • What Is the Experience of Babywearing a NICU Graduate? [Journal Article]
    Nurs Womens Health. 2020 Jun; 24(3):175-184.Miller RR, Bedwell S, … Tow J
  • CONCLUSIONS: The themes identified indicate that babywearing has the potential to address harms-such as stress, fear, depression, anxiety, and posttraumatic stress disorder-that may be experienced by caregivers of infants discharged from the NICU. Babywearing can be used as an intervention to support caregivers and promote positive health outcomes after a NICU discharge.
  • Genetic innovations and our understanding of stillbirth. [Review]
    Hum Genet. 2020 Apr 21 [Online ahead of print]Wilkins-Haug L
  • Stillbirth after 20 weeks gestation happens in 1 in 200 pregnancies and occurs more commonly than neonatal loss and sudden infant death syndrome (SIDs) combined. The stillbirth rate is several times greater in low as opposed to high-resource countries. However, among high-resource countries, although a lower overall stillbirth rate exists, there has been little change for several decades. Molecul…
  • Impact of a national genetic carrier-screening program for reproductive purposes. [Journal Article]
    Acta Obstet Gynecol Scand. 2020 Jun; 99(6):802-808.Singer A, Sagi-Dain L
  • CONCLUSIONS: Our results highlight the impact of a national genetic carrier-screening program. Couples at risk of an affected fetus mostly choose to perform preconception or prenatal diagnosis and to act accordingly. Our country has several characteristics enabling us to achieve this success, including considerable rates of endogamy and consanguineous marriages, increased frequency of founder mutations, and high fertility rates. In addition, wide accessibility of the tests and good compliance of the population must be noted. Still, raising the awareness and continuing education of population and caregivers about the importance and efficiency of carrier screening remains an important issue. Finally, expanding the existing tests into a uniform, wide genetic panel seems to be the next goal.
  • Positioning and baby devices impact infant spinal muscle activity. [Journal Article]
    J Biomech. 2020 May 07; 104:109741.Siddicky SF, Bumpass DB, … Mannen EM
  • Infant positioning in daily life, particularly in relation to active neck and back muscles, may affect spinal development, psychosocial progression, and motor milestone achievement. Yet the impact of infant body position on muscle activity is unknown. The objective of this study was to evaluate neck and back muscle activity of healthy infants in common positions and baby devices. Healthy full-ter…
  • [Clinical practice guidelines for spinal muscular atrophy]. [Journal Article]
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2020 Mar 10; 37(3):263-268.Writing Group For Practice Guidelines For Diagnosis And Treatment Of Genetic Diseases Medical Genetics Branch Of Chinese Medical Association , Pan J, … Wu L
  • Spinal muscular atrophy (SMA) is one of the most common fatal autosomal recessive genetic disorders among infants. It is caused by mutations of motor neuron survival gene 1 (SMN1). The incidence of SMA among newborns is approximately 1/10 000 - 1/6000, and the carrier rate is 1/72 - 1/47 with an ethnic variance. Based on the time of onset and clinical phenotype, SMA can be divided into types I - …
  • Use of the KTP laser in totally endoscopic cholesteatoma surgery. [Journal Article]
    J Laryngol Otol. 2020 Apr; 134(4):362-365.Sharma SD, Swarup A, James AL
  • CONCLUSIONS: The combination of KTP laser use with endoscopic visualisation is effective for minimising the risk of residual disease using a minimally invasive surgical approach. The thin, semi-flexible fibre carrier of the KTP laser is ideally suited to work alongside the endoscope within the narrow confines of the ear canal.
  • GeneReviews®: VLDLR Cerebellar Hypoplasia [BOOK]
    . University of Washington, Seattle: Seattle (WA)Adam MP, Ardinger HH, … Amemiya ABoycott KM, MacDonald SK, … Parboosingh JSBOOK
  • VLDLR cerebellar hypoplasia (VLDLR-CH) is characterized by non-progressive congenital ataxia that is predominantly truncal and results in delayed ambulation, moderate-to-profound intellectual disability, dysarthria, strabismus, and seizures. Children either learn to walk very late (often after age 6 years) or never achieve independent ambulation. Brain MRI findings include hypoplasia of the infer…
  • The biology of ergothioneine, an antioxidant nutraceutical. [Journal Article]
    Nutr Res Rev. 2020 Feb 13 [Online ahead of print]Borodina I, Kenny LC, … Kell DB
  • Ergothioneine (ERG) is an unusual thio-histidine betaine amino acid that has potent antioxidant activities. It is synthesised by a variety of microbes, especially fungi (including in mushroom fruiting bodies) and actinobacteria, but is not synthesised by plants and animals who acquire it via the soil and their diet, respectively. Animals have evolved a highly selective transporter for it, known a…
  • GeneReviews®: FLNB Disorders [BOOK]
    . University of Washington, Seattle: Seattle (WA)Adam MP, Ardinger HH, … Amemiya ARobertson SBOOK
  • The FLNB disorders include a spectrum of phenotypes ranging from mild to severe. At the mild end are spondylocarpotarsal synostosis (SCT) syndrome and Larsen syndrome; at the severe end are the phenotypic continuum of atelosteogenesis types I (AOI) and III (AOIII) and Piepkorn osteochondrodysplasia (POCD). SCT syndrome is characterized by postnatal disproportionate short stature, scoliosis and lo…
  • Co-carriage of Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis among three different age categories of children in Hungary. [Journal Article]
    PLoS One. 2020; 15(2):e0229021.Kovács E, Sahin-Tóth J, … Dobay O
  • CONCLUSIONS: Whereas the carriage rates of S. pneumoniae, H. influenzae and M. catarrhalis clearly decreased with age, that of S. aureus showed an opposite tendency. Multiple carriage was least prevalent if S. aureus was one of the participants. The negative association between this bacterium and the others was statistically significant. For pneumococcus, the overall carriage rate was lower compared to earlier years, and PCV13 serotypes were present in only 6.2% of the children. The majority of H. influenzae isolates was non-typeable and no type b was detected; serotype A was dominant among M. catarrhalis. All four bacteria were more sensitive to antibiotics compared to clinical isolates. No MRSAs were detected, but we found three mupirocin resistant strains. The positive effect of Hib- and PCV-vaccination is undoubted. Continued surveillance of these pathogens is required.
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