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317,536 results
  • The same mutation in a family with adenosine deaminase 2 deficiency. [Review]
    Rheumatol Int 2019Sozeri B, Ercan G, … Doğanay L
  • The deficiency of adenosine deaminase 2 (DADA2) has recently been defined as a monogenetic autosomal recessive autoinflammatory disease. DADA2 is mainly characterized by high fever, livedo racemose, early-onset stroke, mild immunodeficiency and clinically polyarteritis nodosa (PAN)-like symptoms. Mutations in CECR1 (cat eye syndrome chromosome region, candidate 1) are responsible for DADA2. Lived…
  • Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis. [Journal Article]
    Nat Commun 2019; 10(1):4317Garikipati VNS, Verma SK, … Kishore R
  • Circular RNAs are generated from many protein-coding genes, but their role in cardiovascular health and disease states remains unknown. Here we report identification of circRNA transcripts that are differentially expressed in post myocardial infarction (MI) mouse hearts including circFndc3b which is significantly down-regulated in the post-MI hearts. Notably, the human circFndc3b ortholog is also…
  • Takotsubo cardiomyopathy triggered by wasabi consumption: can sushi break your heart? [Journal Article]
    BMJ Case Rep 2019; 12(9)Finkel-Oron A, Olchowski J, … Barski L
  • Takotsubo cardiomyopathy is a left ventricular dysfunction that typically occurs after sudden intense emotional or physical stress and mimics myocardial infarction. We describe a case of a 60-year-old woman that presented to the emergency department with chest pain after she attended a wedding and ate a large amount of wasabi, assuming it to be an avocado. To the best of our knowledge, this is th…
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