- Impact of pelvic biometric measurements, visceral and subcutaneous adipose tissue areas on trifecta outcome and surgical margin status after open radical retropubic prostatectomy. [Journal Article]
- SJScand J Urol 2015; 49(2):108-14
- CONCLUSIONS: Pelvic biometric measurements and adipose tissue area calculations may help in preoperative planning and the management of RP.
- Differential expression of Meis2, Mab21l2 and Tbx3 during limb development associated with diversification of limb morphology in mammals. [Journal Article]
- PlosPLoS One 2014; 9(8):e106100
- Bats are the only mammals capable of self-powered flight using wings. Differing from mouse or human limbs, four elongated digits within a broad wing membrane support the bat wing, and the foot of the…
Bats are the only mammals capable of self-powered flight using wings. Differing from mouse or human limbs, four elongated digits within a broad wing membrane support the bat wing, and the foot of the bat has evolved a long calcar that spread the interfemoral membrane. Our recent mRNA sequencing (mRNA-Seq) study found unique expression patterns for genes at the 5' end of the Hoxd gene cluster and for Tbx3 that are associated with digit elongation and wing membrane growth in bats. In this study, we focused on two additional genes, Meis2 and Mab21l2, identified from the mRNA-Seq data. Using whole-mount in situ hybridization (WISH) we validated the mRNA-Seq results for differences in the expression patterns of Meis2 and Mab21l2 between bat and mouse limbs, and further characterize the timing and location of the expression of these two genes. These analyses suggest that Meis2 may function in wing membrane growth and Mab21l2 may have a role in AP and DV axial patterning. In addition, we found that Tbx3 is uniquely expressed in the unique calcar structure found in the bat hindlimb, suggesting a role for this gene in calcar growth and elongation. Moreover, analysis of the coding sequences for Meis2, Mab21l2 and Tbx3 showed that Meis2 and Mab21l2 have high sequence identity, consistent with the functions of genes being conserved, but that Tbx3 showed accelerated evolution in bats. However, evidence for positive selection in Tbx3 was not found, which would suggest that the function of this gene has not been changed. Together, our findings support the hypothesis that the modulation of the spatiotemporal expression patterns of multiple functional conserved genes control limb morphology and drive morphological change in the diversification of mammalian limbs.
- Antegrade, covered, self-expanding stent as an iliac extension in a bifurcated endograft: a feasible technical maneuver for challenging aortoiliac aneurysmal anatomy. [Case Reports]
- AVAnn Vasc Surg 2011; 25(6):842-5
- CONCLUSIONS: Auto-expandable covered stent-graft with a thinner shaft can be used through a brachial access as an iliac extension of a bifurcated aortic endograft. However, a longer follow-up duration and more cases are necessary to warrant the safety and the durability of such an "off-label" endovascular material assemblage.
- Interfemur variation of bone mineral density in patients receiving high-dose thyroxin therapy. [Journal Article]
- CTCalcif Tissue Int 1998; 63(2):98-101
- In order to evaluate the interfemoral variability of bone mineral density (BMD) in patients receiving thyroxin (T4) replacement therapy, dual-energy X-ray absorptiometry (DXA) was performed on both h…
In order to evaluate the interfemoral variability of bone mineral density (BMD) in patients receiving thyroxin (T4) replacement therapy, dual-energy X-ray absorptiometry (DXA) was performed on both hips and the lumbar spine of 114 individuals. BMD was measured in 47 patients under T4 therapy in suppressive doses because of histologically proven thyroid cancer and 67 age-matched controls free of any known local or generalized disorder that would affect the bones and joints. Variation in BMD between both hips was determined for four different regions of interest, i.e., Ward's triangle, intertrochanteric region, trochanter, and femoral neck. No significant difference in hip BMD was found between patients and controls. Even though some individuals had large interfemoral BMD variation, no significant difference in hip BMD variability between the groups was observed. In patients under suppressive T4 replacement therapy, BMD measurement in one hip is suitable to predict BMD of the other hip and therefore unilateral hip measurement may be adequate.
- [Validity and reproducibility of osteodensitometric DEXA-measurements following total hip endoprosthesis]. [Journal Article]
- ZOZ Orthop Ihre Grenzgeb 1997 Jan-Feb; 135(1):35-9
- For the determination of reproducibility of bone densitometric measurements we performed a measurement according to the DEXA- method. 35 patients after implantation of total hip replacement were exam…
For the determination of reproducibility of bone densitometric measurements we performed a measurement according to the DEXA- method. 35 patients after implantation of total hip replacement were examined with a Lunar DPX-L. We received a maximum reproduction error of 1.2% according to the GRUEN-analysis. The operated hip of 17 patients showed an increase in bone density between 5 and 18% by the implantation of an arthroplasty compared to the preoperative values. The non-operated prosthesis-corrected hip showed a reproduction error of 3.8% in ROI 1 in 17 patients, otherwise a maximum of 1.3%. Considering an interfemoral difference in bone density of up to 20%, differences in periprosthetic bone density of up to 40% compared to the contralateral side can be within the normal range in a retrospective measurement. Therefore retrospective determination of bone density after cementless hip arthroplasty only is of limited value. Only prospective analysis can provide reliable information about the actual loss of bone density.
- Congenital absence of the vagina--results of conservative treatment. [Journal Article]
- EJEur J Obstet Gynecol Reprod Biol 1995; 59(2):183-6
- CONCLUSIONS: Intercourse as a treatment of vaginal atresia can be very successful, especially if practised together with modified mold therapy. A stable sexual relationship--implying a healthy self-concept--appears to be an important determinant of treatment outcome.
- [A case of artero-ureteral fistula. Review of the literature]. [Case Reports]
- JUJ Urol (Paris) 1990; 96(1):55-9
- We report a case of a 78-year old male patient with a history of hematuria. Diagnosis of a shunt between a left common iliac artery aneurysm and the ipsilateral ureter was arrived at on the basis of …
We report a case of a 78-year old male patient with a history of hematuria. Diagnosis of a shunt between a left common iliac artery aneurysm and the ipsilateral ureter was arrived at on the basis of arteriographic findings. Surgery consisted in ligating the left ureter proximal and distal to its communication with the aneurysm (left kidney silent on intravenous urogram), in closing the arterial orifices proximal and distal to the aneurysm, and in constructing an extraanatomical interfemoral bypass. At sixteen months' hindsight, the patient is doing well. Literature is reviewed (24 entries).
- [Crossed iliofemoral bypass]. [Journal Article]
- JCJ Chir (Paris) 1984; 121(5):375-7
- Crossed shunts between the two femoral axes constitute a useful safeguard in unilateral iliac occlusions when the abdominal approach is contraindicated. Hemodynamic considerations suggest the need fo…
Crossed shunts between the two femoral axes constitute a useful safeguard in unilateral iliac occlusions when the abdominal approach is contraindicated. Hemodynamic considerations suggest the need for iliac implantation from the donor side. This simple technique does not complicate the operation and provides a more satisfactory result than the interfemoral shunt.
- [Combined revascularisation of the superficial and deep femoral arteries by vein graft (author's transl)]. [Journal Article]
- NPNouv Presse Med 1979 May 12; 8(21):1753-5
- When venous bypass is indicated in order to reconstruct the femoral bifurcation, or its branches, it is desirable to revascularise the superficial and deep femoral at the same time. There are three t…
When venous bypass is indicated in order to reconstruct the femoral bifurcation, or its branches, it is desirable to revascularise the superficial and deep femoral at the same time. There are three technical possibilities: bifurcated graft, scarf graft, bypass with interfemoral graft. If there is a lack of venous material, the bypass will be mixed: goretex-vein. There are numerous indications for these procedures: obliterative arterial disease with stenosis of the division of the common femoral, repeated of septic surgery of the femoral tripod, aneurysms of traumatic lesions involving the femoral bifurcation.