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25,702 results
  • Ketamine for Treatment-Resistant Mood Disorders. [Review]
    Focus (Am Psychiatr Publ) 2019; 17(1):8-12Park LT, Falodun TB, Zarate CA
  • Strong evidence supports the rapid, although temporary, antidepressant effects of a single intravenous ketamine infusion for treatment-resistant major depressive disorder (MDD) and bipolar depression. Although ketamine has diverse effects on brain neurotransmitters, current theories have implicated N-methyl-d-aspartate antagonist effects at the presynaptic interneuron in mediating its antidepress…
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