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(intraretinal microvascular abnormalities)
94 results
  • Application of optical coherence tomography angiography in diabetic retinopathy: a comprehensive review. [Review]
    Can J Ophthalmol 2019; 54(5):519-528Akil H, Karst S, … Maberley D
  • Optical coherence tomography angiography (OCTA) is a noninvasive method that enables visualization of blood flow within retinal vessels down to the size of capillaries by detecting motion contrast from moving blood cells. OCTA provides a fast and safe procedure to assess retinal microvasculature with higher contrast and resolution than conventional fluorescence angiography. The different capillar…
  • Combined Multimodal Analysis of Peripheral Retinal and Macular Circulation in Diabetic Retinopathy (COPRA Study). [Journal Article]
    Ophthalmol Retina 2019; 3(7):580-588Or C, Das R, … Chakravarthy U
  • CONCLUSIONS: OCTA metrics are indicators of the severity of peripheral retinal nonperfusion. However, the central ischemic index did not exhibit a linear relationship with peripheral capillary nonperfusion. Our findings suggest that a rise in intraocular vascular endothelial growth factor as a consequence of mild peripheral capillary nonperfusion may play a compensatory role in maintaining the central macular microcirculation. Further investigations with studies employing longitudinal design will improve our understanding of the relationship between macular microcirculation and peripheral ischemia.
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