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1,310,330 results
  • Hole Migration In Telomere-Based Oligonucleotide Anions And G-Quadruplexes. [Journal Article]
    Chemistry 2019Li W, Mjekiqi E, … Schlathölter T
  • Vacuum ultraviolet photoionization of a gas-phase oligonucleotide anion leads to the formation of a valence hole. This hole migrates towards an energetically favorable site where it can weaken bonds and ultimately lead to bond cleavage. We have studied VUV photoionization of deprotonated oligonucleotides containing the human telomere sequence dTTAGGG and G-quadruplex structures consisting of four…
  • The Ps and Qs of alarmone synthesis in Staphylococcus aureus. [Journal Article]
    PLoS One 2019; 14(10):e0213630Yang N, Xie S, … Watt RM
  • During the stringent response, bacteria synthesize guanosine-3',5'-bis(diphosphate) (ppGpp) and guanosine-5'-triphosphate 3'-diphosphate (pppGpp), which act as secondary messengers to promote cellular survival and adaptation. (p)ppGpp 'alarmones' are synthesized and/or hydrolyzed by proteins belonging to the RelA/SpoT Homologue (RSH) family. Many bacteria also encode 'small alarmone synthetase' (…
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