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551,888 results
  • Alcohol protects the CNS by activating HSF1 and inducing the Heat Shock Proteins. [Review]
    Neurosci Lett 2019; :134507Pignataro L
  • Although alcohol abuse and dependence have profound negative health consequences, emerging evidence suggests that exposure to low/moderate concentrations of ethanol protects multiple organs and systems. In the CNS, moderate drinking decreases the risk of dementia and Alzheimer's disease. This neuroprotection correlates with an increased expression of the heat shock proteins (HSPs). Multiple epide…
  • MTSS1 hypermethylation is associated with prostate cancer progression. [Journal Article]
    J Cell Physiol 2019Chen J, Huang L, … Tang Z
  • This study was conducted to evaluate the influence of DNA methylation of metastasis suppressor 1 (MTSS1) on prostate cancer (PCa) progression. Forty-nine paired PCa tissue samples and normal tissue samples from The Cancer Genome Atlas were analyzed. Methylome analysis, CpG island arrays and Hierarchical clustering were used to analyze methylation profiles of PCa tissues. MTSS1 methylation level w…
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