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4,394 results
  • Onychocryptosis and asymptomatic external urethritis as complications of oral isotretinoin therapy. [Journal Article]
    BMJ Case Rep 2019; 12(8)Sivaraj K, Friedman J, Morrell D
  • This case report presents a patient who, while undergoing oral isotretinoin therapy for acne vulgaris, developed onychocryptosis and asymptomatic external urethritis. These uncommon adverse events are not well-documented in medical literature. While his urethritis spontaneously resolved, his onychocryptosis symptoms necessitated surgical intervention. This report illustrates both cosmetic and fun…
  • The Role of IL-17 in Papulopustular Rosacea and Future Directions. [Journal Article]
    J Cutan Med Surg 2019; :1203475419867611Amir Ali A, Vender R, Vender R
  • Rosacea is a chronic, progressive, inflammatory condition phenotypically subtyped into diagnostic features, major features, and minor/secondary features. There is currently no cure for rosacea, and it carries a significant negative psychosocial burden for afflicted patients. While there are a number of treatment modalities at the disposal of the clinician, clinical experience has suggested a need…
  • A recalcitrant case of ulcerative lichen planus responsive to leflunomide. [Letter]
    Clin Exp Dermatol 2019Sardana K, Gupta A
  • A 48-year old female presented with violaceous ulcerated lesions present on both legs for 8 years diagnosed as lichen planus(LP). (Fig. 1(a)) Previous treatments included dapsone, oral and topical steroids, methotrexate, isotretinoin, cyclosporine, antibiotics causing modest improvement only. The patient was receiving methotrexate 12.5mg/week for a month when she presented to us and it was contin…
  • Prolonged Serum Alanine Aminotransferase Elevation Associated with Isotretinoin Administration. [Case Reports]
    Case Reports Hepatol 2019; 2019:9270827Nazarian RS, Zheng E, … Wolkoff AW
  • Isotretinoin is a highly effective oral retinoid derivative for severe forms of acne. Despite its high margin of safety, isotretinoin carries a risk of teratogenicity and mild to massive elevations of serum cholesterol and triglyceride levels, as well as infrequent transaminitis. Liver dysfunction induced by isotretinoin is rare but it poses a management dilemma. We describe a 16-year-old male in…
  • Successful treatment of frontal fibrosing alopecia with alitretinoin. [Journal Article]
    Dermatol Ther 2019; :e13037Lee JY, Hong JS, … Lee AY
  • Frontal fibrosing alopecia (FFA) is an inflammatory disorder characterized by scarring alopecia of the frontotemporal scalp, thinning or loss of facial hair, and facial papules. Prompt treatment is essential to prevent permanent hair loss. Although studies have reported the efficacy of oral retinoids (isotretinoin and acitretin) in FFA treatment, a therapeutic role for alitretinoin is known only …
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