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18,499 results
  • Sequential and environmental dependence of conformation in a small opioid peptide. [Journal Article]
    J Org Chem 2019Schwartz AC, Jay DW, … Giuliano MW
  • We report the structural characterization of the -selective endogenous opioid endomorphin-1 (EM-1) via an array of nuclear magnetic resonance experiments in both aqueous conditions, and, for the first time, in isotropic lipid bicelles, which mimic its endogenous environment. Consistent with computationally-derived hypotheses, EM-1 is found to significantly populate a compact, turn-like structure…
  • Analyzing chromosome condensation in yeast by second-harmonic generation microscopy. [Journal Article]
    Curr Genet 2019Yamin K, Assa M, … Onn I
  • Condensation is a fundamental property of mitotic chromosomes in eukaryotic cells. However, analyzing chromosome condensation in yeast is a challenging task while existing methods have notable weaknesses. Second-harmonic generation (SHG) microscopy is a label-free, advanced imaging technique for measuring the surface curve of isotropic molecules such as chromatin in live cells. We applied this me…
  • SERS and plasmonic heating efficiency from anisotropic core/satellite superstructures. [Journal Article]
    Nanoscale 2019Kuttner C, Höller RPM, … Liz-Marzán LM
  • The optical properties of nanoparticle assemblies can be tailored via hybridization of plasmon modes. Isotropic core/satellite superstructures made of spherical nanoparticles are known to exhibit coupled modes with a strongly scattering (radiative) character, and provide hot spots yielding high activity in surface-enhanced Raman scattering (SERS). However, to complement this functionality with pl…
  • Dyakonov-Voigt surface waves. [Journal Article]
    Proc Math Phys Eng Sci 2019; 475(2228):20190317Mackay TG, Zhou C, Lakhtakia A
  • Electromagnetic surface waves guided by the planar interface of an isotropic dielectric medium and a uniaxial dielectric medium, both non-dissipative, were considered, the optic axis of the uniaxial medium lying in the interface plane. Whereas this interface is known to support the propagation of Dyakonov surface waves when certain constraints are satisfied by the constitutive parameters of the t…
  • An Anisotropic Fluid-Solid Model of the Mouse Heart. [Journal Article]
    Comput Cardiol 2009; 36:377-380Carson JP, Kuprat AP, … Einstein DR
  • A critical challenge in biomechanical simulations is the spatial discretization of complex fluid-solid geometries created from imaging. This is especially important when dealing with Lagrangian interfaces, as there must be at a minimum both geometric and topological compatibility between fluid and solid phases, with exact matching of the interfacial nodes being highly desirable. We have developed…
    Ann Stat 2017; 45(2):529-556Cheng D, Schwartzman A
  • A topological multiple testing scheme is presented for detecting peaks in images under stationary ergodic Gaussian noise, where tests are performed at local maxima of the smoothed observed signals. The procedure generalizes the one-dimensional scheme of [31] to Euclidean domains of arbitrary dimension. Two methods are developed according to two different ways of computing p-values: (i) using the …
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