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3,883 results
  • Review: corneal endothelial cell derivation methods from ES/iPS cells. [Review]
    Inflamm Regen 2019; 39:19Hatou S, Shimmura S
  • Globally, approximately 12.7 million people are awaiting a transplantation, while only 185,000 cases of corneal transplantation are performed in a year. Corneal endothelial dysfunction (bullous keratopathy) due to Fuchs' corneal endothelial dystrophy, or insults associated with intraocular surgeries, shared half of all indications for corneal transplantation. Regenerative therapy for corneal endo…
  • Delay in the Diagnosis of APECED: A Case Report and Review of Literature from Iran. [Journal Article]
    Immunol Invest 2019; :1-8Jamee M, Mahdaviani SA, … Velayati A
  • Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) syndrome is a rare monogenic autosomal recessive disorder caused by biallelic mutations in the AIRE (autoimmune regulator) gene. Patients with APECED present with heterogeneous endocrine and non-endocrine manifestations. In this study, we report an Iranian patient who presented with Addison disease, chronic mucocutaneous cand…
    Neurochirurgie 2019Touzé R, Robert M
  • CONCLUSIONS: Many ophthalmic potentially sight-threatening complications occur in patients with craniosynostosis, especially when syndromic. Optic neuropathy, mostly resulting from the papilledema causing optic atrophy, secondary to raised intracranial pressure (ICP), should be diagnosed early, in order to promptly lower the ICP. Cyclovertical and horizontal strabismus and refractive errors are frequent in unicoronal synostosis (anterior plagiocephaly) and syndromic craniosynostosis. Exorbitism, encountered in some cases of syndromic craniofacial synostosis, leads to exposure keratopathy, which requires aggressive management to avoid severe irremediable corneal complications. Amblyopia can complicate asymmetrical optic neuropathy, corneal opacity, strabismus, or refractive errors. If undiagnosed and untreated at a young age, it results in permanent visual impairment.Children with craniosynostosis require a multidisciplinary care network including a pediatric ophthalmologist. Systematic ophthalmological follow-up enables papilledema to be diagnosed and amblyopia to be diagnosed and treated, in order to avoid visual impairment.
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