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27,737 results
  • Follicular occlusion disorders in Down syndrome patients. [Journal Article]
    Pediatr Dermatol 2019Firsowicz M, Boyd M, Jacks SK
  • Disorders involving follicular occlusion, such as hidradenitis suppurativa, folliculitis, acneiform eruptions, and pilonidal cysts, have shown an increased prevalence in the Down syndrome (DS) population, but there are limited published data examining this association. We conducted a retrospective chart review of 243 DS patients presenting to a pediatric dermatology clinic to further examine the …
  • Contemporary management of actinic keratosis. [Journal Article]
    J Dermatolog Treat 2019; :1-12Navarrete-Dechent C, Marghoob AA, Marchetti MA
  • Actinic keratosis (AK) is a skin lesion characterized by intraepithelial keratinocyte dysplasia and molecular alterations shared with normal chronically sun-damaged skin and squamous cell carcinoma (SCC). AK can undergo spontaneous regression, stable existence, or malignant transformation to cutaneous SCC with progression rates to SCC ranging from 0% to 0.5% per lesion-year and AK spontaneous reg…
  • Skin changes in the obese patient. [Review]
    J Am Acad Dermatol 2019; 81(5):1037-1057Hirt PA, Castillo DE, … Keri JE
  • Obesity is a worldwide major public health problem with an alarmingly increasing prevalence over the past 2 decades. The consequences of obesity in the skin are underestimated. In this paper, we review the effect of obesity on the skin, including how increased body mass index affects skin physiology, skin barrier, collagen structure, and wound healing. Obesity also affects sebaceous and sweat gla…
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