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(ketoconazole systemic †)
788 results
  • Quantitative Prediction of CYP3A4- and CYP3A5-Mediated Drug Interactions. [Journal Article]
    Clin Pharmacol Ther 2019Guo Y, Lucksiri A, … Hall SD
  • We verified a physiologically-based pharmacokinetic (PBPK) model to predict cytochrome P450 3A4/5-mediated drug-drug interactions (DDIs). A midazolam (MDZ)-ketoconazole (KTZ) interaction study in 24 subjects selected by CYP3A5 genotype, and liquid chromatography and mass spectroscopy quantification of CYP3A4/5 abundance from independently acquired and genotyped human liver (n = 136) and small int…
  • Cutaneous candidiasis - an evidence-based review of topical and systemic treatments to inform clinical practice. [Review]
    J Eur Acad Dermatol Venereol 2019; 33(10):1863-1873Taudorf EH, Jemec GBE, … Saunte DML
  • Cutaneous candidiasis is a common skin disease, and several treatments have been investigated within the last fifty years. Yet, systematic reviews are lacking, and evidence-based topical and systemic treatment strategies remain unclear. Thus, the aim of this review was to summarize efficacy and adverse effects of topical and oral therapies for cutaneous candidiasis in all age groups. Two individu…
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