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24 results
  • Amylin induces hypoglycemia in mice. [Journal Article]
    An Acad Bras Cienc 2013; 85(1):349-54Guerreiro LH, Da Silva D, … Lima LM
  • Amylin is a 37-aminoacid pancreatic protein that exerts control over several metabolic events such as glycemia and lacticemia. Amylin has long been shown to induce increases in arterial plasma glucose. We decided to investigate whether amylin plays additional roles in the glucose metabolism. We evaluated glucose homeostasis using whole blood from the tail tip of fasting, conscious, unrestrained n…
  • Blood glucose and lactate levels during hemorrhagic shock reversion by hypertonic NaCl solution. [Journal Article]
    Braz J Med Biol Res 1994; 27(5):1255-67Lopes LR, Curi R, Lopes OU
  • 1. Several studies have shown that in irreversible hemorrhagic shock the liver is one of the first vital organs to present metabolic alterations accompanied by an increase in lacticemia. Intravenous infusion of hypertonic solutions increases mesenteric flow as well as liver perfusion, an effect which can be blocked by vagotomy. 2. In the present study we investigate the possible role of the incre…
  • The limiting effect of dichloroacetate on endotoxin-induced liver damage in starved rats. [Journal Article]
    J Surg Res 1994; 56(3):216-20Irita K, Okabe H, … Yoshitake J
  • Dichloroacetate has been shown to have therapeutic effects on sepsis and endotoxin shock and to reduce liver damage in rats intoxicated with ethanol or carbon tetrachloride. In this study, the effect of dichloroacetate on endotoxin hepatitis was investigated. Endotoxin hepatitis was induced by an intraperitoneal coadministration of 50 micrograms/kg lipopolysaccharide from Escherichia coli, and 20…
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