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38,353 results
  • Effects of Cu(II) on the aggregation of amyloid-β. [Review]
    J Biol Inorg Chem 2019Weibull MGM, Simonsen S, … Hemmingsen L
  • Aberrant aggregation of the Aβ protein is a hallmark of Alzheimer's disease (AD), but no complete characterization of the molecular level pathogenesis has been achieved. A promising hypothesis is that dysfunction of metal ion homeostasis, and consequently, the undesired interaction of metal ions with Aβ, may be central to the development of AD. Qualitatively, most data indicate that Cu(II) induce…
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