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(laparosalpingo oophorectomy)
34,858 results
  • Ovariectomy Influences Cognition and Markers of Alzheimer's Disease. [Journal Article]
    J Alzheimers Dis 2019Agca C, Klakotskaia D, … Agca Y
  • Alzheimer's disease (AD) is one of the most devastating and costly diseases, and prevalence of AD increases with age. Furthermore, females are twice as likely to suffer from AD compared to males. The cessation of reproductive steroid hormone production during menopause is hypothesized to cause this difference. Two rodent AD models, APP21 and APP+PS1, and wild type (WT) rats underwent an ovariecto…
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