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660 results
  • Comments to the letter to the editor of Dr Sweta Subhadarshani. [Journal Article]
    J Eur Acad Dermatol Venereol 2019Naafs B, Alemu Belachew W
  • We thank dr Sweta Subhadarshani for his complements1 and for his addition to our article2 . We would like to make a few comments: He is right that there are more presentations of clinical leprosy than we mention in our paper. It is a continuous scale, just to mention a few: low resistant T and BT/BB, BB/BL and sub polar LL, histoid leprosy and lepra bonita. It is a gliding scale and each subtype …
  • The Spectrum of SPTA1-Associated Hereditary Spherocytosis. [Journal Article]
    Front Physiol 2019; 10:815Chonat S, Risinger M, … Kalfa TA
  • Hereditary spherocytosis (HS) is the most common red blood cell (RBC) membrane disorder causing hereditary hemolytic anemia. Patients with HS have defects in the genes coding for ankyrin (ANK1), band 3 (SLC4A1), protein 4.2 (EPB42), and α (SPTA1) or β-spectrin (SPTB). Severe recessive HS is most commonly due to biallelic SPTA1 mutations. α-spectrin is produced in excess in normal erythroid cells,…
  • Risk of disability among adult leprosy cases and determinants of delay in diagnosis in five states of India: A case-control study. [Journal Article]
    PLoS Negl Trop Dis 2019; 13(6):e0007495Srinivas G, Muthuvel T, … Kasang C
  • CONCLUSIONS: Patient delay is the major reason for risk of disability (G2D/G1D) among adult leprosy patients. A patient delay of more than 3 months from the notice of first symptom is a significant indicator for the disabilities among adult leprosy patients. Early case detection campaigns like active surveys in endemic spots should be done periodically as this can reduce delays and promote early diagnosis. Additionally, the program should lay greater emphasis on raising community awareness regarding the disease. Also, health care provider delay of more than 1 month have been significant risk factors for disability among adult leprosy cases. Hence, periodical capacitation of all HCPs including private practitioners would significantly contribute to reduce diagnostic delay and promote timely referral and early detection.
  • A dissimulate presentation of histoid Hansen's disease in the form of erythema nodosum leprosum. [Case Reports]
    Int J Mycobacteriol 2019 Apr-Jun; 8(2):208-210Pathania V, Oberoi B, … Shankar P
  • Hansen's disease is a chronic infectious granulomatous disease with varied clinical presentation. Histoid Hansen's disease is an important emerging lepromatous subset of Hansen's disease known to mimic varied dermatoses. Occurrence of reactions, especially erythema nodosum leprosum (ENL), is rare in this form of leprosy. We report a case of Histoid Hansen's disease with initial presentation of EN…
  • [Orientation of primary care in actions to control leprosy: factors relating to professionals]. [Journal Article]
    Gac Sanit 2019Figueiredo Vieira N, Moura Lanza F, … Lana FCF
  • CONCLUSIONS: Professional experience in the Family Health Strategy and leprosy care is crucial for the service to be a provider of control actions oriented according to the essential and derived attributes of primary health care. Brazil has made progress in reducing the incidence of leprosy; however, it is necessary to increase the effectiveness of health surveillance, as a means of early detection and training of professionals.
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