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(lidocaine prilocaine)
1,825 results
  • Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in adult surgical patients: a network meta-analysis. [Review]
    Cochrane Database Syst Rev 2019; 12:CD003006Forget P, Borovac JA, … Pace NL
  • CONCLUSIONS: Results from both NMA and pair-wise meta-analysis indicate that the risk of developing TNS after spinal anaesthesia is lower when bupivacaine, levobupivacaine, prilocaine, procaine, and ropivacaine are used compared to lidocaine. The use of 2-chloroprocaine and mepivacaine had a similar risk to lidocaine in terms of TNS development after spinal anaesthesia. Patients should be informed of TNS as a possible adverse effect of local anaesthesia with lidocaine and the choice of anaesthetic agent should be based on the specific clinical context and parameters such as the expected duration of the procedure and the quality of anaesthesia. Due to the very low- to moderate-quality evidence (GRADE), future research efforts in this field are required to assess alternatives to lidocaine that would be able to provide high-quality anaesthesia without TNS development. The two studies awaiting classification and one ongoing study may alter the conclusions of the review once assessed.
  • Local dermal application of a compound lidocaine cream in pain management of cancer wounds. [Journal Article]
    Braz J Med Biol Res 2019; 52(11):e8567Peng L, Zheng HY, Dai Y
  • The aim of this study was to explore the analgesic effect of local application of compound lidocaine/prilocaine cream on cancer wounds during wound care in order to reduce the amount of morphine intake or completely replace the systemic morphine administration and optimize the protocol for cancer wound pain management. All patients were enrolled with a visual analog scale (VAS) pain score ≥4. Bef…
  • Topical anesthetics for pediatric laser treatment. [Journal Article]
    J Cosmet Laser Ther 2019; 21(7-8):417-421Stevic M, Vlajkovic A, … Simic D
  • Topical anesthetic agent causes transient insensibility to pain in a limited area of skin, and provides effective anesthesia in a short onset time, short duration, with seldom local or systemic side effects on intact skin and is simple to use. Topical formulations may offer significant benefits for prevention of procedural pain. Currently, they are considered to be the most effective anesthesia f…
  • [Intoxication with prilocaine/lidocaine can cause serious methemoglobinemia]. [Case Reports]
    Lakartidningen 2019; 116Kjellgard C, Westphal S, Flisberg A
  • Prilocaine/lidocaine is widely used as local anesthetic in children for cannulation and minor surgical procedures. Usually it is unproblematic but it is important to adhere to recommended dose to avoid serious complications. Excessive amount of prilocaine/lidocaine, large application area, prolonged application time or repeated application can, especially in infants, cause methemoglobinemia with …
  • Intravenous Regional Anesthesia: A Historical Overview and Clinical Review. [Review]
    J Anesth Hist 2019; 5(3):99-108Löser B, Petzoldt M, … Goerig M
  • Intravenous regional anesthesia (IVRA) is an established, safe and simple technique, being applicable for various surgeries on the upper and lower limbs. In 1908, IVRA was first described by the Berlin surgeon August Bier, hence the name "Bier's Block". Although his technique was effective, it was cumbersome and fell into disuse when neuroaxial and percutaneous plexus blockades gained widespread …
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