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271,230 results
  • Novel pararosaniline based optical sensor for the determination of sulfite in food extracts. [Journal Article]
    Spectrochim Acta A Mol Biomol Spectrosc 2019; 226:117643Bener M, Şen FB, Apak R
  • Sulfite, which is a protective agent in various food industries, also is known as an allergen. Therefore, sulfite content in food must be monitored and controlled. In this context, a novel optical sensor is designed for simple, rapid and sensitive determination of the sulfite content in food samples. Acidified pararosaniline (PRA) hydrochloride reagent in cationic form was immobilized on the surf…
  • Pharmacokinetics of PEGylated recombinant human endostatin in rhesus monkeys. [Journal Article]
    Life Sci 2019; :116967Guo L, Li Z, … Luo Y
  • To investigate the pharmacokinetics of PEGylated recombinant human endostatin (M2ES) in rhesus monkey. M2ES was administered to rhesus monkeys by intravenous bolus injection, and serum M2ES concentration was determined by a self-developed ELISA assay. Pharmacokinetic parameters were calculated using a non-compartmental model of WinNonlin V2.1A software. The standard curve of self-developed ELISA …
  • Synergistic Coordination of Chromatin Torsional Mechanics and Topoisomerase Activity. [Journal Article]
    Cell 2019; 179(3):619-631.e15Le TT, Gao X, … Wang MD
  • DNA replication in eukaryotes generates DNA supercoiling, which may intertwine (braid) daughter chromatin fibers to form precatenanes, posing topological challenges during chromosome segregation. The mechanisms that limit precatenane formation remain unclear. By making direct torque measurements, we demonstrate that the intrinsic mechanical properties of chromatin play a fundamental role in dicta…
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