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(liothyronine sodium)
31,066 results
  • Individualised requirements for optimum treatment of hypothyroidism: complex needs, limited options. [Review]
    Drugs Context 2019; 8:212597Hoermann R, Midgley JEM, … Dietrich JW
  • Levothyroxine (LT4) therapy has a long history, a well-defined pharmacological profile and a favourable safety record in the alleviation of hypothyroidism. However, questions remain in defining the threshold for the requirement of treatment in patients with subclinical hypothyroidism, assessing the dose adequacy of the drug, and selecting the best treatment mode (LT4 monotherapy versus liothyroni…
  • Age-Related Resistance to Thyroid Hormone Action. [Review]
    Drugs Aging 2019Mooradian AD
  • The age-related resistance to thyroid hormones (THs) explains the paucity of symptoms and signs of hyperthyroidism in older adults and may partly explain the myriad of symptoms and signs of hypothyroidism in biochemically euthyroid older people. This review considers the available data on the mechanisms underlying TH resistance with aging and compares these physiologic changes with the changes ob…
  • Prevalence and Risk Factors of Thyroid Dysfunction in Older Adults in the Community. [Journal Article]
    Sci Rep 2019; 9(1):13156Diab N, Daya NR, … Selvin E
  • Prevalence estimates and evidence informing treatment targets for thyroid dysfunction largely come from studies of middle-aged adults. We conducted a cross-sectional analysis to determine the prevalence of thyroid dysfunction and risk factors for abnormal thyroid tests in participants aged ≥65 in the Atherosclerosis Risk in Communities (ARIC) study (N = 5,392). We measured serum concentrations of…
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