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508,065 results
  • Establishment of a Mouse Model for Post-Inflammatory Hyperpigmentation. [Journal Article]
    Pigment Cell Melanoma Res. 2020 Jul 04 [Online ahead of print]Nakano S, Abe Y, … Suzuki T
  • Post-inflammatory hyperpigmentation (PIH) is a common cutaneous condition that can cause a disfigured appearance. However, the pathophysiology of PIH remains poorly understood, at least in part, because an appropriate animal model for research has not been established. In order to analyze the pathomechanism of PIH, we successfully induced PIH in a hairless version of transgenic mice (hk14-SCF Tg/…
  • Multiple strategies for maintaining stable partial nitritation of low-strength ammonia wastewater. [Journal Article]
    Sci Total Environ. 2020 Jun 29; 742:140542.Sui Q, Jiang L, … Wei Y
  • Stable production of nitrite is an essential technical challenge for mainstream anaerobic ammonia oxidation (Anammox). Due to difficulties in the stable inhibition of nitrite oxidizing bacteria (NOB) and maintenance of long-term partial nitritation (PN), integrated multiple, rather than a single, controlling strategies were preferred especially in a continuous-flow treatment system. A mathematica…
  • Solubility of two Polymorphs of Tolbutamide in n-Propanol: Comparison of Methods. [Journal Article]
    J Pharm Sci. 2020 Jul 02 [Online ahead of print]Zeng L, Rasmuson ÅC, Svärd M
  • The solid-liquid solubility of two polymorphs of the title compound has been measured in n-propanol over the temperature range (278 K to 303 K) by an isothermal, gravimetric method and a low heating rate polythermal method. Due to marked differences in the settling behavior of crystals of the two polymorphs in the investigated solvent, it is found that the low heating rate polythermal method give…
  • Concurrent Antisolvent Electrospraying: A Novel Continuous Crystallization Technique. [Journal Article]
    J Pharm Sci. 2020 Jul 02 [Online ahead of print]Perge L, Gröls J, … Castro-Dominguez B
  • Pharmaceutical co-crystals (CCs) are multicomponent materials that enable the development of novel therapeutic products by enhancing the properties of active pharmaceutical ingredients, such as solubility, permeability and bioavailability. Currently, CCs are a commercial reality; nonetheless, their industrial production remains a challenge due to problems related to scale up, control and mode of …
  • Advances in lipidomics. [Review]
    Clin Chim Acta. 2020 Jul 02 [Online ahead of print]Avela HF, Sirén H
  • The present article examines recently published literature on lipids, mainly focusing on research involving glycero-, glycerophospho- and sphingo-lipids. The primary aim is identification of distinct profiles in biologic lipidomic systems by ultra-high-performance liquid chromatography (UHPLC) coupled with mass spectrometry (MS, tandem MS) with multivariate data analysis. This review specifically…
  • Liquid biopsy in ovarian cancer. [Journal Article]
    Clin Chim Acta. 2020 Jul 02 [Online ahead of print]Bhardwaj BK, Thankachan S, … Suresh PS
  • Ovarian cancer is typically diagnosed at an advanced stage and poses a significant challenge to treatment and recovery. Relapsed ovarian cancer and chemoresistance of ovarian tumor cells are other clinical challenges. Liquid biopsy is an essential non-invasive diagnostic test that evaluates circulating tumor cells and tumor DNA, as well as other blood markers that may be useful in guiding precisi…
  • Change of tear lipid mediators in a post-trabeculectomy cohort. [Journal Article]
    Ocul Surf. 2020 Jul 02 [Online ahead of print]Ambaw YA, Wong T, … Tong L
  • CONCLUSIONS: In this 3-years study, trabeculectomy reduced the tear level of pro-inflammatory lipid mediators. Patients who required needling of the bleb to maintain surgical success may have a chronic underlying inflammatory process associated with fibrosis.
  • Non-volatile disinfection byproducts are far more toxic to mammalian cells than volatile byproducts. [Journal Article]
    Water Res. 2020 Jun 18; 183:116080.Wu QY, Liang ZF, … Huang WC
  • Water is often chlorinated to protect public health, but chlorination causes harmful disinfection byproducts to form. Currently available in vitro assays generally determine non-volatile disinfection byproduct (NVDBP) toxicities because of the limitation of pretreatments used, but chemical analyses and regulations are focused on volatile disinfection byproducts (VDBPs) such as trihalomethanes. Th…
  • Spatiotemporally tracking of nano-biofilaments inside the nuclear pore complex core. [Journal Article]
    Biomaterials. 2020 Jun 23; 256:120198.Mohamed MS, Hazawa M, … Wong RW
  • Nuclear pore complex (NPC) is a gating nanomachine with a central selective barrier composed mainly of Nups, which contain intrinsically disordered (non-structured) regions (IDRs) with phenylalanine-glycine (FG) motifs (FG-NUPs). The NPC central FG network dynamics is poorly understood, as FG-NUPs liquid-liquid phase separation (LLPS) have evaded structural characterization. Moreover, the working…
  • Analysis of effects and indications of cryosurgery for oral mucoceles. [Journal Article]
    J Stomatol Oral Maxillofac Surg. 2020 Jul 01 [Online ahead of print]Tsunoda N, Kawai T, … Yamada H
  • Cryosurgery is a recognized method for the treatment of mucoceles in the oral cavity. In this study, cryosurgery was used for mucoceles at the lip or buccal mucosa, and the effect and the indication were evaluated clinically. The subjects were patients with a clinical diagnosis of mucocele on the lip or buccal mucosa and who chose cryosurgery after procedures for both surgical excision and cryosu…
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