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(local recurrence)
143,952 results
  • Chondroblastomas presenting in adulthood: a study of 39 patients with emphasis on histologic features and skeletal distribution. [Journal Article]
    Histopathology 2019John I, Inwards CY, … Fritchie KJ
  • CONCLUSIONS: CB in patients >20 years of age more frequently involves the short bones of the hands/feet and flat bones compared to those arising in their younger counterparts. A subset may harbor extensive serpiginous or psammomatous calcification rather than the classic chicken-wire pattern. Though the overall local recurrence rate in adulthood is roughly 10%, all three patients with recurrent disease had tumors involving flat bones suggesting that tumors arising in these sites may behave more aggressively. This article is protected by copyright. All rights reserved.
  • PROMIS Function Scores Are Lower in Patients Who Underwent More Aggressive Local Treatment for Desmoid Tumors. [Journal Article]
    Clin Orthop Relat Res 2019Newman ET, Lans J, … Calderon SL
  • CONCLUSIONS: Patients treated with local modalities (surgery and/or radiation, with or without additional systemic therapy) did not experience improved EFS as compared with those treated without local modalities; this was the case for both the primary and the recurrent tumor cohorts. However, PROMIS function scores were lowest among patients who underwent two or more surgical interventions and among those treated with surgery and radiation at any time, suggesting that more aggressive local treatment may be associated with poorer long-term functional outcomes. Prospective collection of patient-reported outcomes data at multiple time points will allow for more direct correlations between treatment modality and impact on function and will help to elucidate the ideal management strategy for these benign but often-symptomatic tumors.
  • Colorectal Cancer in the Elderly Patient: The Role of Neo-adjuvant Therapy. [Journal Article]
    Open Med (Wars) 2019; 14:607-612Dodaro CA, Calogero A, … Sagnelli C
  • CONCLUSIONS: The effect of pathological downstaging amounted to 58.8%, including cPR. The pathologic complete remission occurred in 8.8% of cases.The outcomes of neoadjuvant therapy can be achieved when this treatment is associated with correct surgical technique with TME and the prognosis is defined by an anatomopathological examination performed according to Quirke's protocol.
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