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(lung protective strategy)
1,223 results
  • Intraoperative Mechanical Ventilation and Postoperative Pulmonary Complications after Cardiac Surgery. [Journal Article]
    Anesthesiology 2019Mathis MR, Duggal NM, … Engoren MC
  • CONCLUSIONS: The authors identified an intraoperative lung-protective ventilation bundle as independently associated with pulmonary complications after cardiac surgery. The findings offer insight into components of protective ventilation associated with adverse outcomes and may serve as targets for future prospective interventional studies investigating the impact of specific protective ventilation strategies on postoperative outcomes after cardiac surgery.
  • MiR-150 attenuates LPS-induced acute lung injury via targeting AKT3. [Journal Article]
    Int Immunopharmacol 2019; 75:105794Li P, Yao Y, … Chen Y
  • Acute lung injury (ALI) and its severe manifestation of acute respiratory distress syndrome (ARDS) in human lung are induced by inflammatory cytokines and endogenous factors such as miRNAs. However, the role of miR-150 in lipopolysaccharide (LPS)-induced ALI is not clear. Here, we found miR-150 expression was significantly reduced in the serum of patients with ARDS, and negatively associated with…
  • CD200R1 regulates eosinophilia during pulmonary fungal infection in mice. [Journal Article]
    Eur J Immunol 2019; 49(9):1380-1390Salek-Ardakani S, Bell T, … Hussell T
  • CD200 receptor 1(CD200R1) signalling limits myeloid cell responses and reduces autoimmunity, alloimmunity and viral-mediated immunopathology, but has never been examined in the context of eosinophilic inflammation. Susceptibility to lung fungal infection is associated with T-helper 2 (Th2) cytokine dominated responses and strong eosinophilic pathology. Blockade of CD200R1 enhances type I cytokine…
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