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35 results
  • A new blood parasite of leaf warblers: molecular characterization, phylogenetic relationships, description and identification of vectors. [Journal Article]
  • PVParasit Vectors 2018 Oct 04; 11(1):538
  • Chagas CRF, Bukauskaitė D, … Valkiūnas G
  • CONCLUSIONS: Haemoproteus homopalloris n. sp. is the third haemoproteid, which is described from and is prevalent in wood warblers. Phylogenetic analysis identified a clade containing seven haemoproteids, which are characterised by pale staining of the macrogametocyte cytoplasm and with ookinetes maturing exceptionally rapidly (between 1 to 1.5 h after exposure to air). Both these features may represent valuable phylogenetic characters. Studies targeting mechanisms of sporogonic development of haemoproteids remain uncommon and should be encouraged. Culicoides nubeculosus is an excellent experimental vector of the new parasite species.
  • Plasmodium transmission blocking activities of Vernonia amygdalina extracts and isolated compounds. [Journal Article]
  • MJMalar J 2015 Jul 25; 14:288
  • Abay SM, Lucantoni L, … Habluetzel A
  • CONCLUSIONS: Vernonia amygdalina leaves contain molecules affecting multiple stages of Plasmodium, evidencing its potential for drug discovery. Chemical modification of the identified hit molecules, in particular vernodalol, could generate a library of druggable sesquiterpene lactones. The development of a multistage phytomedicine designed as preventive treatment to complement existing malaria control tools appears a challenging but feasible goal.
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