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9,452 results
  • Human proteinase 3 resistance to inhibition extends to alpha-2 macroglobulin. [Journal Article]
    FEBS J 2020N'Guessan K, Grzywa R, … Korkmaz B
  • Neutrophils contain at least four serine endopeptidases namely elastase (NE), proteinase 3 (PR3), cathepsin G (CatG) and NSP4, which contribute to the regulation of infection and of inflammatory processes. In physiological conditions, endogenous inhibitors including α2-macroglobulin (α2-M), serpins (α1-proteinase inhibitor (α1-PI)), monocyte neutrophil elastase inhibitor (MNEI), α1-antichymotryps…
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