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(magnesia and alumina tablets )
6 results
  • Evaluation of buffering capacity and acid neutralizing-pH time profile of antacids. [Journal Article]
    J Formos Med Assoc 1998; 97(10):704-10Lin MS, Sun P, Yu HY
  • The antacid properties of seven antacids listed in the hospital formulary of a medical center were evaluated with in vitro tests. These included not only the preliminary antacid test and acid-neutralizing capacity test as described in the United States Pharmacopeia (USP XXIII), but also a buffering pH profile test. The preliminary antacid test measured the final pH of a 10-mL solution of 0.5 N HC…
  • Effect of antacids on activity of oral hypoglycemics. [Journal Article]
    J Pharm Sci 1981; 70(6):621-4Said SA, Abdullah ME
  • The effect of some antacids on the dissolution and hypoglycemic activity of acetohexamide, tolazamide, and tolbutamide tablets was investigated, as was the adsorption of the three drugs onto the antacids. The dissolution rates of the three drugs in the presence of magnesium oxide, aluminum hydroxide, magnesium carbonate, and calcium carbonate increased (0.5-1 hr) and then plateaued or decreased (…
  • Digoxin degradation in acidic dissolution medium. [Journal Article]
    J Pharm Sci 1980; 69(4):410-3Sonobe T, Hasumi S, … Nagai T
  • The release of digoxin and its simultaneous conversion to digoxigenin bisdigitoxoside, digoxigenin monodigitoxoside, and digoxigenin in a USP dissolution test medium were followed by high-pressure liquid chromatography. Two products, Tablets A and B, were manufactured by solvent deposition and simple blending methods, respectively. Tablet A released digoxin faster than Tablet B in distilled water…
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