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92,892 results
  • Post transfusion malaria: current state in Tunisia (new case reported in 2016). [Journal Article]
    Tunis Med 2019; 97(1):149-152Fakhfakh N, Kallel A, … Kallel K
  • Since the elimination of indigenous transmission of malaria in Tunisia in 1979, almost all the cases observed are imported cases related to travel. We report a recent case of highly probable post-transfusion malaria (PTM) in a 27-year-old Tunisian who has never left Tunisia. He has been allografted and has received of the globular pellets and the platelet units along with his hospitalization. The…
  • Recent development of leucyl-tRNA synthetase inhibitors as antimicrobial agents. [Review]
    Medchemcomm 2019; 10(8):1329-1341Zhang P, Ma S
  • Aminoacyl-tRNA synthetases (aaRSs) widely exist in organisms and mediate protein synthesis. Inhibiting these synthetases can lead to the termination of protein synthesis and subsequently achieve antibacterial and antiparasitic purposes. Moreover, the structures of aaRSs found in eukaryotes have considerable structural differences compared to those in prokaryotes, based on which it is possible to …
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