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628 results
  • Plasma Eicosanoid Profile in Plasmodium vivax Malaria: Clinical Analysis and Impacts of Self-Medication. [Journal Article]
    Front Immunol 2019; 10:2141Abreu-Filho PG, Tarragô AM, … Malheiro A
  • The participation of cytokines and chemokines in Plasmodium vivax malaria (Pv-malaria) activates the immune response and thus causes the production of several inflammatory mediators. This process is already well-established, but little is known about eicosanoids in malaria physiopathology, especially in regards to inflammation and immunity. Malaria is an acute febrile syndrome similar to any othe…
  • When glycosylated hemoglobin is a true roller coaster. [Journal Article]
    Porto Biomed J 2019 Jan-Feb; 4(1):e30Peixoto FR, Martins CAF, Couto PDM
  • Corticosteroids negatively interfere with glycemic control. We report a case of a patient with type 2 diabetes mellitus with poor glycemic control caused by coercion to intramuscular corticosteroid administration at work. The relationship established with the patient allowed her to speak openly about her working environment, allowing her to trust the information provided by her family physician e…
  • Genetic risk for Alzheimer's dementia predicts motor deficits through multi-omic systems in older adults. [Journal Article]
    Transl Psychiatry 2019; 9(1):241Tasaki S, Gaiteri C, … Bennett DA
  • Alzheimer's disease manifests with both cognitive and motor deficits. However, the degree to which genetic risk of Alzheimer's dementia contributes to late-life motor impairment, and the specific molecular systems underlying these associations, are uncertain. Here, we adopted an integrative multi-omic approach to assess genetic influence on motor impairment in older adults and identified key mole…
  • Opioids Use and Abuse: Prescription Practice, Attitude, and Beliefs among Doctors of Karachi. [Journal Article]
    Cureus 2019; 11(7):e5253Majid Z, Tanveer M, … Imtiaz F
  • Background Opioid analgesics, also known as narcotics, are medicinal drugs used primarily for the management of pain secondary to any type of cancer, severe injury or surgery. Due to the ease of availability, opioids are commonly abused. In 2015, reported deaths exceeded 33,000 Americans from opioid overdose. A survey in 2013 revealed nearly 1.6 million Pakistanis abusing prescription opioids for…
  • Medical marijuana. What can we learn from the experiences in Canada, Germany and Thailand? [Journal Article]
    Int J Drug Policy 2019; 74:47-51Rehm J, Elton-Marshall T, … Manthey J
  • Cannabis policies are changing globally, and medical marijuana programs are part of these changes. Drawing from the examples of two high-income (Canada, an early adopter of medical marijuana, and Germany, a late adopter) and one middle-income (Thailand) countries, we illustrate two main pressures underlying these recent changes. First, in many high-income countries, cannabis has been used to self…
  • Refinements to captive chimpanzee (Pan troglodytes) care: a self-medication Paradigm. [Journal Article]
    Anim Welf 2018; 27(4):327-341Webb SN, Hau J, Schapiro SJ
  • In an effort to enhance welfare, behavioural management continually refines methods of non-human primate (NHP) care. Chimpanzees (Pan troglodytes) are one of the most cognitively complex captive NHPs and they have been observed to self-medicate in the wild. The population of captive chimpanzees in the US is aged (due to a breeding moratorium instituted in 1998) and will progressively require more…
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