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159 results
  • Analysis of the aortic root in patients with tetralogy of Fallot undergoing early repair: form follows function. [Journal Article]
  • JTJ Thorac Cardiovasc Surg 2014; 148(4):1555-9
  • François K, Creytens D, … Bové T
  • CONCLUSIONS: Infants with ToF undergoing repair around 6 months old already had limited features of aortic wall degradation at surgery. Echocardiographic follow-up, however, demonstrated significant reductions in the indexed aortic diameters. We presume that early repair of ToF will prevent a disproportionate aortic diameter increase by halting progression of the limited histologic changes potentially predisposing to late aortic dilatation.
  • Age is a risk factor for maladaptive changes of the pulmonary root in rats exposed to increased pressure loading. [Journal Article]
  • CPCardiovasc Pathol 2012 May-Jun; 21(3):199-205
  • Vida VL, Rizzo S, … Basso C
  • CONCLUSIONS: The pulmonary artery wall seems to present maladaptive architectural changes in the media when exposed to systemic pressure. The PAB-related increase of the apoptotic index seems to reflect an accelerated involution of the pulmonary root's media. The physiologic higher degree of elastic fibers disarray in adult rats can possibly influence the worst adaptation of the pulmonary arterial wall to a systemic pressure load.
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