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210 results
  • Drug interactions of meglitinide antidiabetics involving CYP enzymes and OATP1B1 transporter. [Review]
    Ther Adv Endocrinol Metab 2018; 9(8):259-268Pakkir Maideen NM, Manavalan G, Balasubramanian K
  • Meglitinides such as repaglinide and nateglinide are useful to treat type 2 diabetes patients who follow a flexible lifestyle. They are short-acting insulin secretagogues and are associated with less risk of hypoglycemia, weight gain and chronic hyperinsulinemia compared with sulfonylureas. Meglitinides are the substrates of cytochrome P450 (CYP) enzymes and organic anion transporting polypeptide…
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