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3,166 results
  • Gonadotrophins for ovulation induction in women with polycystic ovary syndrome. [Meta-Analysis]
    Cochrane Database Syst Rev 2019; 1:CD010290Weiss NS, Kostova E, … van Wely M
  • CONCLUSIONS: There may be little or no difference in live birth, incidence of multiple pregnancy, clinical pregnancy rate, or miscarriage rate between urinary-derived gonadotrophins and recombinant follicle stimulating hormone in women with polycystic ovary syndrome. For human menopausal gonadotropin or highly purified human menopausal gonadotrophin versus urinary follicle stimulating hormone we are uncertain whether one or the other improves or lowers live birth, incidence of multiple pregnancy, clinical pregnancy rate, or miscarriage rate. We are uncertain whether any of the interventions reduce the incidence of ovarian hyperstimulation syndrome. We suggest weighing costs and convenience in the decision to use one or the other gonadotrophin. In women with clomiphene citrate failure, gonadotrophins resulted in more live births than continued clomiphene citrate without increasing multiple pregnancies.
  • [Effect of GnRHa controlled ovarian hyperstimulation on mouse embryo implantation and its mechanism]. [Journal Article]
    Sheng Li Xue Bao 2018; 70(5):489-496Wu Q, Xu HZ, … Song CM
  • The purpose of the present study was to investigate the effects and underlying mechanism of gonadotropin-releasing hormone agonist (GnRHa) controlled ovarian hyperstimulation (COH) on embryo implantation in mice. Forty female Kunming mice aged 9 weeks were randomly divided into two groups (control and COH groups). The COH group received intraperitoneal (i.p.) injections of aminocyclin acetate (Gn…
  • Highly Purified Human Menopausal Gonadotropin (Menopur®): A Profile of Its Use in Infertility. [Review]
    Clin Drug Investig 2018; 38(11):1077-1084Deeks ED
  • Menopur® is a highly purified, urine-derived, human menopausal gonadotropin containing both follicle stimulating hormone (FSH) and luteinizing hormone (LH) activity. It is an effective option for controlled ovarian stimulation (COS) in assisted reproductive technology protocols and for ovulation induction (OI) in anovulatory infertility, and is associated with a different endocrine profile from t…
  • Neonate female to male ratio after assisted reproduction following antagonist and agonist protocols. [Journal Article]
    Medicine (Baltimore) 2018; 97(38):e12310Al-Jaroudi D, Salim G, Baradwan S
  • We retrospectively compared neonatal sex after antagonist- versus long-stimulation protocols followed by fresh in vitro fertilization (IVF) or fresh intracytoplasmic sperm injection (ICSI) with either protocol. We reviewed data for 762 IVF/ICSI cycles in 2015, including 23 IVF procedures. We summarized sex outcomes in the entire cohort, and for the additional subgroups: embryo transfer day and nu…
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