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6 results
  • Three-year-old child with meroacrania - neurological signs. [Case Reports]
    Brain Dev 2011; 33(1):86-9Funayama CA, Pfeifer LI, … Neto AM
  • Neurological findings in a three-year-old child with meroacrania provide new insights into how the nervous system develops and functions in the absence of superior levels of control from the time of origin. The girl is the first child of a non-consanguineous white Brazilian couple, born at term, weighing 2650 g and measuring 44 cm in length. Upon examination at 43 months, she had quadriplegia, gl…
  • Neonate with meroacrania: radiological findings and review of the literature. [Case Reports]
    Diagn Interv Radiol 2009; 15(4):232-5Yildirim H, Koç M, … Aygün D
  • Acrania is a developmental abnormality characterized by a partial or complete absence of calvaria with complete but abnormal development of brain tissue. Acrania is a relatively common malformation and affects about 1 in 1000 newborns. Meroacrania refers to absence of the cranium with the exception of the occipital bone. Brain stem and cerebellum develop normally, but cerebral parenchyma tissue i…
  • Sex, neural tube defects, and multisite closure of the human neural tube. [Journal Article]
    Am J Med Genet 1995; 58(4):332-6Seller MJ
  • While neural tube defects (NTD) overall have a female sex bias, this does not apply to all sites along the neuraxis. The findings regarding sex and NTD in a series of midtrimester fetuses are reviewed, and then analysed in terms of the recent hypothesis that during embryogenesis of the human neural tube there are multiple closure sites, rather than a single zipping up process. Females more often …
  • Neural tube defects and sex ratios. [Journal Article]
    Am J Med Genet 1987; 26(3):699-707Seller MJ
  • The sex ratio of 147 fetuses with presumed multifactorial neural tube defect (NTD) was studied. Overall, the ratio (males:females) was 0.73 with expected female excess. However, when the NTDs were subdivided according to the site of the lesion, the sex ratios varied. Total craniorachischisis, anencephaly with cervical spina bifida, holoacrania, and thoracic spina bifida showed a greater female ex…
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