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826 results
  • Theoretical study on the metabolic mechanisms of levmepromazine by cytochrome P450. [Journal Article]
    J Mol Model 2016; 22(10):237Wang Y, Chen Q, … Xue Y
  • Levomepromazine, an "older" typical neuroleptic, is widely applied in psychiatry for the treatment of schizophrenia. The biotransformation of Levomepromazine remains elusive up to now, but found to result in the formation of different derivatives that may contribute to the therapeutic and/or side-effects of the parent drug. The present work aims to resolve the metabolic details of Levomepromazine…
  • Levomepromazine for nausea and vomiting in palliative care. [Review]
    Cochrane Database Syst Rev 2015; (11):CD009420Cox L, Darvill E, Dorman S
  • CONCLUSIONS: As in the initial review, we identified no published randomised controlled trials examining the use of levomepromazine for the management of nausea and vomiting in adults receiving palliative care, and our conclusion (that further studies of levomepromazine and other antiemetic agents are needed to provide better evidence for their use in this setting) remains unchanged. We did, however, identify one ongoing study that we hope will contribute to the evidence base for this intervention in future updates of this review.
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