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56,757 results
  • PRMT1 activates myogenin transcription via MyoD arginine methylation at R121. [Journal Article]
    Biochim Biophys Acta Gene Regul Mech 2019; :194442Liu Q, Zhang XL, … Zhang Y
  • MyoD is a determining transcription factor involved in myogenic cell differentiation. Post translational modifications of MyoD, including phosphorylation and acetylation, can regulate its transcription activity. Inhibition of protein arginine methyltransferase 1 (PRMT1) leads to insufficient muscle differentiation. However, little is known about arginine methylation in regulating MyoD activity. H…
  • Commentary on the effects of RANKL inhibition on bone mass and muscle strength? [Journal Article]
    J Diabetes Investig 2019Hwang JS, Lien SA, Jiang YD
  • Osteoporosis and sarcopenia, or interpreted as osteo-sarcopenia, is a major public health problem and the social economic burden in many countries and also in Asia. It's the most common metabolic bone and muscle disorder in elderly, especially in female. Osteoporosis is a pathologic process by a decrease in bone mass and deterioration in skeletal microarchitecture, accompanied by a progressive an…
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