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1,670,938 results
  • Treatment-Resistant Bacterial Keratitis: Challenges and Solutions. [Review]
    Clin Ophthalmol 2020; 14:287-297Egrilmez S, Yildirim-Theveny Ş
  • Bacterial keratitis is an important ophthalmic emergency and one of the most common causes of corneal blindness. The main causes of treatment resistance in bacterial keratitis are failure to eliminate predisposing factors, misdiagnosis and mistreatment. At first, exogenous, local and systemic predisposing factors that disturbing ocular surface must be eliminated to improve corneal ulcers and to p…
  • Critical review on the mechanistic photolytic and photocatalytic degradation of triclosan. [Review]
    J Environ Manage 2020; 260:110101Solá-Gutiérrez C, Schröder S, … Ortiz I
  • The environmentally extended presence of triclosan, TCS, component of many pharmaceutical and personal care products, and its known persistent character have awoke the scientific and social concern leading to the study of effective remediation techniques. Advanced oxidation techniques stand out for the effectiveness in degrading many persistent compounds, and as a result, they have been addressed…
  • Structural Basis for the Antibiotic Resistance of Eukaryotic Isoleucyl-tRNA Synthetase. [Journal Article]
    Mol Cells 2020Chung S, Kim S, … Cho Y
  • Pathogenic aminoacyl-tRNA synthetases (ARSs) are attractive targets for anti-infective agents because their catalytic active sites are different from those of human ARSs. Mupirocin is a topical antibiotic that specifically inhibits bacterial isoleucyltRNA synthetase (IleRS), resulting in a block to protein synthesis. Previous studies on Thermus thermophilus IleRS indicated that mupirocin-resistan…
  • [A preliminary study on the safety of berberine solution in rabbit eyes with topical application]. [Journal Article]
    Zhonghua Yan Ke Za Zhi 2020; 56(2):131-137Zhang Y, Bai F, Tao H
  • Objective: To study the safety of topical berberine solution in rabbit eyes and its effect on corneal epithelial repair in rabbit eyes. Methods: Experimental Study. Ninety-two Japanese rabbits were randomly divided into two groups by random number table method: the general group (32 rabbits, 64 eyes) and the corneal injury group (60 rabbits, 60 eyes).The general groups were further divided into…
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