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31,667 results
  • Phenolic constituents from the twigs of Betula schmidtii collected in Goesan, Korea. [Journal Article]
    Phytochemistry 2019; 167:112085Park KJ, Cha JM, … Lee KR
  • Six undescribed phenolic derivatives along with thirty two known compounds were isolated from the twigs of Betula schmidtii. The chemical structures were characterized through extensive spectroscopic analysis and chemical methods. All known compounds were first isolated in this plant. The anti-inflammatory effect of the isolates was tested by measuring nitric oxide production in lipopolysaccharid…
  • Two distinct actin waves correlated with turns-and-runs of crawling microglia. [Journal Article]
    PLoS One 2019; 14(8):e0220810Yang TD, Park K, … Lee KJ
  • Freely crawling cells are often viewed as randomly moving Brownian particles but they generally exhibit some directional persistence. This property is often related to their zigzag motile behaviors that can be described as a noisy but temporally structured sequence of "runs" and "turns." However, its underlying biophysical mechanism is largely unexplored. Here, we carefully investigate the collec…
  • A single-cell transcriptome atlas of the adult human retina. [Journal Article]
    EMBO J 2019; :e100811Lukowski SW, Lo CY, … Wong RC
  • The retina is a specialized neural tissue that senses light and initiates image processing. Although the functional organization of specific retina cells has been well studied, the molecular profile of many cell types remains unclear in humans. To comprehensively profile the human retina, we performed single-cell RNA sequencing on 20,009 cells from three donors and compiled a reference transcript…
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