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16 results
  • Simultaneous micronization and purification of bioactive fraction by supercritical antisolvent technology. [Journal Article]
    J Adv Pharm Technol Res 2017 Apr-Jun; 8(2):52-58Hiendrawan S, Veriansyah B, … Tjandrawinata RR
  • Simultaneous micronization and purification of DLBS3233 bioactive fraction, a combination of two Indonesian herbals Lagerstroemia speciosa and Cinnamomum burmannii has been successfully performed via supercritical anti-solvent (SAS) technology. The objective of the present study was to investigate the effectiveness of SAS technology to micronize and reduce coumarin content of DLBS3233. The effect…
  • Hollow crystalline straws of diclofenac for high-dose and carrier-free dry powder inhaler formulations. [Journal Article]
    Int J Pharm 2016; 502(1-2):170-80Yazdi AK, Smyth HD
  • CONCLUSIONS: Hollow needles of DF were precipitated. With similar particle size distributions, the jet-milled DFNa sample from the collection bag, and the DF sample from the cyclone were used for further characterization. Despite different deposition patterns in the Next Generation Impactor, the DF hollow needles had a comparable respirable fraction percentage to the jet-milled DF and DFNa particles. However, the jet-milled DF formulation had the best in vitro aerodynamic performance.Hollow, crystalline needles of DF were formed and possessed promising aerosol performance in comparison with the jet-milled powders.
  • The use of human amnion/chorion membrane in the clinical setting for lower extremity repair: a review. [Review]
    Clin Podiatr Med Surg 2015; 32(1):135-46Zelen CM, Snyder RJ, … Li WW
  • Unsuccessful healing represents a significant medical dilemma for both patients and clinicians and create a financial burden on the health care system. Despite the efforts of physicians, many injuries fail to heal with standard care alone. For decades human amniotic membrane composed of both amnion and chorion has shown remarkable therapeutic potential, but only recent preservation methods have a…
  • Enhancement of dissolution rate of mitotane and warfarin prepared by using microemulsion systems. [Journal Article]
    Colloids Surf B Biointerfaces 2011; 85(2):366-72Lin YH, Chen YS, … Chen LJ
  • Micronization is the most effective way to enhance the dissolution rate of poorly water-soluble drugs and bioavailability in human body. Microemulsion systems were applied to micronize mitotane and warfarin by cooling method and solvent diffusion process. The triangle phase diagram of the ternary benzyl alcohol+sodium dodecyl sulfate (SDS)+water system was investigated at six different temperatur…
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