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226,084 results
  • Test of a clinical model of poor physical health and suicide: The role of depression, psychosocial stress, interpersonal conflict, and panic. [Journal Article]
  • JAJ Affect Disord 2019 May 31; 257:404-411
  • Black J, Bond MA, … Black E
  • CONCLUSIONS: Firstly, the study sample was primarily Caucasian, limiting its generalizability. Secondly, causal inferences should be interpreted with caution, due to the quasi-experimental design. Thirdly, these data were self-reported, which create response biases since suicidal ideation is stigmatized.These findings highlight the importance of considering interpersonal factors as potential mediators in the relationship between poor physical health, mental illness, and suicide. Clinically, the impact of an active major depressive episode on an individual who is struggling with a serious physical illness may be strongly predictive of suicidal ideation.
  • Circular Zymogens of Human Ribonuclease 1. [Journal Article]
  • PSProtein Sci 2019 Jul 15
  • Windsor IW, Graff CJ, Raines RT
  • The endogenous production of enzymes as zymogens provides a means to control catalytic activities. Here, we describe the heterologous production of ribonuclease 1 (RNase 1), which is the most prevale…
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