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(mometasone inhalation )
153 results
  • Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level. [Randomized Controlled Trial]
    N Engl J Med 2019; 380(21):2009-2019Lazarus SC, Krishnan JA, … National Heart, Lung, and Blood Institute AsthmaNet
  • CONCLUSIONS: The majority of patients with mild, persistent asthma had a low sputum eosinophil level and had no significant difference in their response to either mometasone or tiotropium as compared with placebo. These data provide equipoise for a clinically directive trial to compare an inhaled glucocorticoid with other treatments in patients with a low eosinophil level. (Funded by the National Heart, Lung, and Blood Institute; SIENA ClinicalTrials.gov number, NCT02066298.).
  • Repurposing drugs as inhaled therapies in asthma. [Review]
    Adv Drug Deliv Rev 2018; 133:19-33Anderson SD
  • For the first 40 years of the 20th century treatment for asthma occurred in response to an asthma attack. The treatments were given by injection or orally and included the adrenergic agonists adrenalin/epinephrine and ephedrine and a phosphodiesterase inhibitor theophylline. Epinephrine became available as an aerosol in 1930. After 1945, isoprenaline, a non-selective beta agonist, became availabl…
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