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(multiple organ dysfunction syndrome)
19,932 results
  • Clinical Course and Outcome of Community-Acquired Bacterial Meningitis in Cancer Patients. [Journal Article]
    Adv Exp Med Biol 2019Paciorek M, Bednarska A, … Horban A
  • The aim of the study was to determine the course and outcome of bacterial meningitis (BM) in patients with cancer. We retrospectively reviewed files of patients with community-acquired BM, hospitalized in a single neuroinfection center between January 2010 and December 2017. There were 209 patients included in the analysis: 28 had cancer (9 women, 19 men; median age 76, IQR 67-80 years) and 181 w…
  • Invasive fungal wound infection in an otherwise healthy trauma patient (Mucor Trauma). [Case Reports]
    Trauma Case Rep 2019; 24:100251Wilson W, Ali-Osman F, … Mangram A
  • CONCLUSIONS: Mucormycosis is a rare infection that has been increasingly documented in trauma patients. Early recognition together with prompt debridement and antifungal therapy is key to successful management. Understanding risk factors for post-traumatic mucormycosis should raise our index of suspicion and prompt early diagnosis and initiation of treatment. Aggressive debridement is a critical component of appropriate management due to the angioinvasive spread of the mucor fungi. This means frequent debridement beyond the demarcation of gangrenous tissue. The management of our patient demonstrates the importance of early recognition of the clinical presentation, prompt initiation of antifungal therapy, and aggressive debridement of the wound.
  • The SOFA score-development, utility and challenges of accurate assessment in clinical trials. [Review]
    Crit Care 2019; 23(1):374Lambden S, Laterre PF, … Francois B
  • The Sequential Organ Failure Assessment or SOFA score was developed to assess the acute morbidity of critical illness at a population level and has been widely validated as a tool for this purpose across a range of healthcare settings and environments.In recent years, the SOFA score has become extensively used in a range of other applications. A change in the SOFA score of 2 or more is now a defi…
  • [Clinical characteristics and repair effect of 136 patients with electric burns of upper limb]. [Journal Article]
    Zhonghua Shao Shang Za Zhi 2019; 35(11):784-789Wen YZ, Zhang PH, … Huang XY
  • CONCLUSIONS: Upper extremity electric burn often occurs in children, electricians, and rural migrant workers with high rate of amputation. Teachers and parents should strengthen safety education for children and manage power source of life well. Workers should improve safety awareness and operate standardly. Fasciotomy for relaxation should be performed for electric burn wound as soon as possible, and flap grafting can effectively repair wound after early debridement. The function recovery of affected upper limb repaired with free flap grafting is better.
  • The Interactions between Respiratory and Cardiovascular Systems in Systolic Heart Failure. [Journal Article]
    J Appl Physiol (1985) 2019Cross TJ, Kim CH, … Lalande S
  • Heart failure (HF) is a complex and multifaceted disease. The disease affects multiple organ systems, including the respiratory system. This review provides three unique examples illustrating how the cardiovascular and respiratory systems interrelate due to the pathology of HF. Specifically, these examples outline the impact of HF pathophysiology on: (i) respiratory mechanics and the mechanical "…
  • [Research progress in the heatstroke-induced myocardial injury]. [Journal Article]
    Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2019; 31(10):1304-1306Lou Y, Lin H, … Li H
  • Heat stroke is the most serious type of heat-related diseases, and the induced multiple organ dysfunction syndrome (MODS) is an important cause of death for heat stroke patients. The cardiovascular system is one of the important targets of heat injury. Studies have reported that heat stress can lead to myocardial inhibition, abnormal heart conduction and blood flow redistribution, thus changing t…
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