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1,995 results
  • Nasal decolonization of Staphylococcus aureus in orthopedic surgeons using mupirocin and chlorhexidine. [Journal Article]
    Am J Infect Control 2019Castro-Martínez AG, Garza-González E, … Camacho-Ortiz A
  • Nasal mucosa colonization by Staphylococcus aureus is a risk factor for hospital-acquired infections. This study examined the effectiveness of a decolonization strategy on orthopedic surgeons in a teaching hospital. S aureus colonization was detected in 43.2% of the surgeons, 25% of which were methicillin-resistant S aureus strains. Eradication was documented in 61.53% of the subjects who complet…
  • Elimination of Staphylococcus aureus nasal carriage in intensive care patients lowers infection rates. [Journal Article]
    Eur J Clin Microbiol Infect Dis 2019Akhtar Danesh L, Saiedi Nejad Z, … Ghaznavi-Rad E
  • This study surveys the clinical relevance of the nasal Staphylococcus aureus colonization status on intensive care unit (ICU)-acquired S. aureus infections and compares molecular characteristics of isolates from the nose and infectious sites. The 390 patients included comprised 278 non-carriers and 112 carriers. Among the carriers, 56 were decolonized with mupirocin. Decolonization was verified t…
  • Liposomal mupirocin holds promise for systemic treatment of invasive Staphylococcus aureus infections. [Journal Article]
    J Control Release 2019; 316:292-301Goldmann O, Cern A, … Medina E
  • Staphylococcus aureus is a major cause of severe invasive infections. The increasing incidence of infections caused by antibiotic-resistant strains such as methicillin-resistant S. aureus (MRSA), calls for exploration of new approaches to treat these infections. Mupirocin is an antibiotic with a unique mode of action that is active against MRSA, but its clinical use is restricted to topical admin…
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