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27,545 results
  • Acute Neuromuscular Disorders in the Pediatric Intensive Care Unit. [Journal Article]
    J Child Neurol 2019; :883073819871437Harrar DB, Darras BT, Ghosh PS
  • CONCLUSIONS: Although acute and acute-on-chronic neuromuscular disorders are encountered relatively rarely in the PICU, familiarity with the presenting features of these disorders is important in facilitating timely diagnosis. This, in turn, enables the institution of effective management strategies, thereby avoiding complications associated with diagnostic delays.
  • Understanding Enterovirus D68-Induced Neurologic Disease: A Basic Science Review. [Review]
    Viruses 2019; 11(9)Hixon AM, Frost J, … Tyler KL
  • In 2014, the United States (US) experienced an unprecedented epidemic of enterovirus D68 (EV-D68)-induced respiratory disease that was temporally associated with the emergence of acute flaccid myelitis (AFM), a paralytic disease occurring predominantly in children, that has a striking resemblance to poliomyelitis. Although a definitive causal link between EV-D68 infection and AFM has not been une…
  • Enterovirus D68 serosurvey: evidence for endemic circulation in the Netherlands, 2006 to 2016. [Journal Article]
    Euro Surveill 2019; 24(35)Karelehto E, Koen G, … Wolthers K
  • BackgroundEnterovirus D68 (EV-D68) has caused major outbreaks of severe respiratory illness worldwide since 2010.AimOur aim was to evaluate EV-D68 circulation in the Netherlands by conducting a serosurvey of EV-D68 neutralising antibodies (nAb) among the Dutch general population.MethodsWe screened 280 sera from children and adults in the Netherlands and used two independent sets of samples collec…
  • Acute flaccid myelitis: Rehabilitation challenges and outcomes in a pediatric cohort. [Journal Article]
    J Pediatr Rehabil Med 2019Melicosta ME, Dean J, … Sadowsky C
  • CONCLUSIONS: Children with flaccid paralysis due to AFM undergoing structured, comprehensive rehabilitation interventions, even when these are initiated long after paralysis onset, can make significant neurologic and functional gains. Recovery of function and prevention of comorbidities are the main therapeutic targets for interventions in this population.
  • [A case of severe acute flaccid myelitis requiring continuous mechanical ventilation]. [Journal Article]
    Rinsho Shinkeigaku 2019Matsuo K, Koga M, … Fukusako T
  • Many cases of acute flaccid paralysis occurred during an enterovirus D68 (EV-D68) outbreak in North America in the fall of 2014, and this epidemic has been newly defined as a distinct disease entity named acute flaccid myelitis (AFM). This disease entity is relatively popular among pediatricians, whereas it remains little-known among neurologists in Japan. We reported a 7-year-old girl with AFM, …
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