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1,392 results
  • An exploration of the role of Sertoli cells on fetal testis development using cell ablation strategy. [Journal Article]
    Mol Reprod Dev 2020; 87(2):223-230Wang YQ, Cheng JM, … Liu YX
  • Sertoli cells (SCs) are presumed to be the center of testis differentiation because they provide both structural support and biological regulation for spermatogenesis. Previous studies suggest that SCs control germ cell (GC) count and Leydig cell (LC) development in mouse testes. However, the regulatory role of SCs on peritubular myoid (PTM) cell fate in fetal testis has not been clearly reported…
  • Immunolocalization of aromatase P450 in the epididymis of Podarcis sicula and Rattus rattus. [Journal Article]
    Eur J Histochem 2020; 64(1)Rosati L, Prisco M, … Andreuccetti P
  • The goal of this study was to evaluate P450 aromatase localization in the epididymis of two different vertebrates: the lizard Podarcis sicula, a seasonal breeder, and Rattus rattus, a continuous breeder. P450 aromatase is a key enzyme involved in the local control of spermatogenesis and steroidogenesis and we proved for the first time that this enzyme is represented in the epididymis of both P. s…
  • EBV-associated myoid tumor with lipoblast-like cells in a patient with normal immunity. [Case Reports]
    Int J Clin Exp Pathol 2019; 12(7):2733-2742Wu R, Tang W, … Li Y
  • EBV-associated myoid tumor (EBVMT) comprises a specific group of soft tissue tumors with divergent histologic appearances, which typically occur in immunocompromised patients. To the best of our knowledge, there have been no previous reported of EBVMT in patients with normal immunity. EBVMT with lipoblast-like cells (EBVMT-LIC) is an extremely rare variant of EBVMT. Here, a male patient with norm…
  • Mammary myoid hamartomas: reports of two cases and a review of the literature. [Review]
    Int J Clin Exp Pathol 2019; 12(7):2398-2404Xia T, Qin C, … Xiao X
  • The purpose of this report is to determine the clinicopathological and immuno-phenotypical characteristics of myoid hamartoma of the breast (MHB). The clinical data, histological morphology, and immunohistochemical results of 2 patients diagnosed with MHB were analyzed, and 15 cases of MHB reported in China were reviewed. Both patients were female, aged 28 and 35 years old, and their lesions were…
  • The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty. [Journal Article]
    Cell Stem Cell 2020Guo J, Nie X, … Cairns BR
  • The human testis undergoes dramatic developmental and structural changes during puberty, including proliferation and maturation of somatic niche cells, and the onset of spermatogenesis. To characterize this understudied process, we profiled and analyzed single-cell transcriptomes of ∼10,000 testicular cells from four boys spanning puberty and compared them to those of infants and adults. During p…
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