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189,642 results
  • Severe Abdominal Manifestations in Juvenile Dermatomyositis. [Journal Article]
    J Pediatr Gastroenterol Nutr 2020; 70(2):247-251Besnard C, Gitiaux C, … Bader-Meunier B
  • Juvenile dermatomyositis (JDM) is a rare and heterogeneous pediatric-onset idiopathic inflammatory myopathy. Gastrointestinal (GI) involvement occurs in 22% to 37% of JDM patients but has only been described in case reports. In this retrospective, single-center, observational study, we aimed to assess the causes and management of severe GI manifestations in JDM patients. We studied a cohort of 9 …
  • Human fetal mesoangioblasts reveal tissue-dependent transcriptional signatures. [Journal Article]
    Stem Cells Transl Med 2020Ronzoni FL, Lemeille S, … Jaconi ME
  • Mesoangioblasts (MABs) derived from adult skeletal muscles are well-studied adult stem/progenitor cells that already entered clinical trials for muscle regeneration in genetic diseases; however, the transcriptional identity of human fetal MABs (fMABs) remains largely unknown. Herein we analyzed the transcriptome of MABs isolated according to canonical markers from fetal atrium, ventricle, aorta, …
  • Exercise therapy in muscle diseases: open issues and future perspectives. [Journal Article]
    Acta Myol 2019; 38(4):233-238Siciliano G, Schirinzi E, … Ricci G
  • In muscle diseases different molecular mechanisms are responsible, by distinct cellular pathways, of muscle fibers contraction insufficiency and exercise intolerance. Depending on that, exercise therapy is a promising avenue to efficaciously counteract the loss of muscle fiber function or also the secondary effects due to the sedentary lifestyle as a consequence of the motor impairment. It has be…
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