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987 results
  • Enhancement of opioid antinociception by nicotine. [Journal Article]
    J Pharmacol Exp Ther 2019de Moura FB, Withey SL, Bergman J
  • Nicotine can produce antinociception in preclinical pain models; however, the ability of nicotine to augment the antinociceptive effects of opioid agonists has not been investigated. The present experiments were conducted to determine how nicotine modifies the effects of opioid agonists differing in efficacy. Male squirrel monkeys responded for the delivery of milk under a fixed ratio 10 schedule…
  • Sex differences in the response to opioids for pain relief: A systematic review and meta-analysis. [Review]
    Pharmacol Res 2019; :104447Pisanu C, Franconi F, … Agabio R
  • There are conflicting results about sex differences in the response to opioids for pain control and the role of potential influencing factors of these differences has not been investigated. We meta-analyzed differences and similarities between men and women in opioid response for pain control and investigated the potential influence of baseline pain intensity, age, body weight, and other factors …
  • Investigation of analgesic dose of nalbuphine combined with remifentanil after radical gastrectomy. [Journal Article]
    Exp Ther Med 2019; 18(3):1633-1638Zhang Y, Zhang R, Ding N
  • Clinical analgesic effect of different doses of nalbuphine combined with remifentanil on postoperative gastric cancer patients was explored. One hundred cases of gastric cancer patients treated from December 2014 to December 2016 in the Xiangyang No. 1 People's Hospital were selected and separated into group A and group B. The dose in group A was 0.2 mg/kg of nalbuphine plus 0.2 µg/kg of remifent…
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