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419 results
  • Drinking Levels and Profiles of Alcohol Addicted Rats Predict Response to Nalmefene. [Journal Article]
  • FPFront Pharmacol 2019; 10:471
  • Foo JC, Vengeliene V, … Spanagel R
  • CONCLUSIONS: Our results suggest that nalmefene reduces alcohol intake during a relapse-like situation but effectiveness can differ greatly at the individual level. However, who responds may be informed by examining drinking profiles and rats that show high drinking levels prior to treatment are more likely to respond to nalmefene.
  • Selecting an appropriate alcohol pharmacotherapy: review of recent findings. [Journal Article]
  • COCurr Opin Psychiatry 2019; 32(4):266-274
  • Castrén S, Mäkelä N, Alho H
  • CONCLUSIONS: Three new published RCTs focus on baclofen and naltrexone. These results are consistent with old findings demonstrating that naltrexone reduces heavy drinking. Several RCT on baclofen do not support the use of baclofen for treatment of AUD. Encouraging results have been reported for topiramate, gabapentin and also varenicline, which might be useful in patients with comorbid nicotine dependence.
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