- Velopharyngeal closure analysis using four-dimensional computed tomography: a pilot study of healthy volunteers and adult patients with cleft palate. [Journal Article]
- BMBMC Med Imaging 2019 Jul 08; 19(1):54
- CONCLUSIONS: Although the radiation exposure cannot be ignored, our novel evaluation method using 320-ADCT enables more detailed evaluation of VPC than nasopharyngoscopy. Future studies should investigate the relationship between 320-ADCT findings and speech pathology evaluations.
- Unilateral Vocal Fold Immobility in Children. [Review]
- OCOtolaryngol Clin North Am 2019; 52(4):681-692
- Unilateral vocal fold paralysis (UVFP) in children may cause dysfunction in voice, swallowing, and breathing, thus influencing all components of laryngeal function. UVFP in children is usually the re…
Unilateral vocal fold paralysis (UVFP) in children may cause dysfunction in voice, swallowing, and breathing, thus influencing all components of laryngeal function. UVFP in children is usually the result of iatrogenic injury. The approach to patients with suspected UVFP should involve a detailed patient history, a focused physical examination with flexible nasopharyngoscopy, and relevant imaging if the cause of UVFP is uncertain. Management aims to strengthen voice, decrease aspiration, and improve quality of life. Laryngeal reinnervation is becoming more common, potentially offering permanent improvement in vocal and swallowing function through increasing bulk and tone to the paralyzed vocal fold.
- Endobronchial, laryngeal and mediastinal melanoma: a rare constellation of metastatic disease. [Journal Article]
- BCBMJ Case Rep 2019 May 08; 12(5)
- A 45-year-old man presents with acute respiratory failure. Imaging revealed a left mainstem endobronchial mass with subcarinal lymphadenopathy, but no other evidence of a primary tumour. An incidenta…
A 45-year-old man presents with acute respiratory failure. Imaging revealed a left mainstem endobronchial mass with subcarinal lymphadenopathy, but no other evidence of a primary tumour. An incidental laryngeal nodule was found during bronchoscopy. Biopsies of this lesion by nasopharyngoscopy and subcarinal lymph nodes via mediastinoscopy were performed. Histopathological and immunohistochemical examination showed evidence of melanoma in both samples. Mutational analysis identified the presence of a BRAFV600E mutation. The patient underwent bronchoscopic ablation of the left mainstem endobronchial tumour with laser therapy followed by initiation of encorafenib and binimetinib combination therapy. The patient remains alive at 4 months after initial presentation of disease. This case adds to the body of literature highlighting the clinical heterogeneity and challenges of the management of metastatic pulmonary melanoma. To the best of our knowledge, this simultaneous constellation of metastasis has not been described before.
- [Analysis of sensitization spectrum and clinical features of children with adenoid hypertrophy and perennial rhinitis]. [Journal Article]
- LCLin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019; 33(4):351-353
- CONCLUSIONS: Allergic rhinitis is closely related to adenoid hypertrophy, and the effect of allergen on the clinical manifestations of patients with adenoid hypertrophy should be emphasized.
- StatPearls: Flexible Nasopharyngoscopy [BOOK]
- BOOKStatPearls Publishing: Treasure Island (FL)
- Flexible nasopharyngoscopy (also called fiberoptic nasendoscopy/flexible nasolaryngoscopy/flexible fiberoptic nasopharyngolaryngoscopy) is an essential skill for any otorhinolaryngologist (ENT surgeo…
Flexible nasopharyngoscopy (also called fiberoptic nasendoscopy/flexible nasolaryngoscopy/flexible fiberoptic nasopharyngolaryngoscopy) is an essential skill for any otorhinolaryngologist (ENT surgeon). It is a diagnostic procedure used for examination of the nose, throat, and airway. Fiber-optic imaging became prominent in the 1950s due to the innovations of Hopkins and Stortz. The first medically functioning fiberoptic scope was designed in 1963 by Hirschowitz.
- Reversible conductive hearing impediments among patients with severe brain injury. [Journal Article]
- DRDisabil Rehabil 2019 Apr 05; :1-4
- CONCLUSIONS: Many patients with severe brain injury have reversible and treatable impairments that cause potential conductive hearing loss. Routine otoscopic examination and treatment if required, that is, removal of impacted cerumen or middle ear drainage, have rehabilitating and general health benefits. Implications for rehabilitation Auditory stimulation was suggested for rehabilitation in patients with severe traumatic brain injury. Many patients have cerumen and/or otitis media with effusion causing conductive hearing impairment as well as general health issues. Both aural impediments are diagnosed by routine otoscopy, are easily treated, and may affect rehabilitation.
- Voice and swallowing dysfunction in X-linked dystonia parkinsonism. [Journal Article]
- LLaryngoscope 2019 Mar 19
- CONCLUSIONS: Swallowing and voice impairment in XDP is not well characterized and presents a more distinctive phenomenology than other neurological disorders, with a unique set of challenges for treatment. This is the first study to systematically evaluate laryngeal and pharyngeal dysfunction in XDP patients and correlate with QOL measures.
- Cost-effectiveness of Screening for Nasopharyngeal Carcinoma among Asian American Men in the United States. [Journal Article]
- OHOtolaryngol Head Neck Surg 2019; 161(1):82-90
- CONCLUSIONS: Although screening for NPC with plasma Epstein-Barr virus DNA for 50-year-old Asian American men may result in earlier detection, in this study it was unlikely to be cost-effective. Screening may be reasonable for certain subpopulations at higher risk for NPC, but clinical studies are necessary before implementation.
- The effect of hypertrophied tonsils on the velopharyngeal function in children with normal palate. [Journal Article]
- IJInt J Pediatr Otorhinolaryngol 2019; 119:59-62
- CONCLUSIONS: hypertrophied tonsils may impair velopharyngeal function in children with normal palate by hindering palatal elevation. Tonsillectomy is a beneficial procedure for such patients as it can improve the velopharyngeal closure and speech resonance.
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- Mandibular advancement device therapy for obstructive sleep apnea: a prospective study on predictors of treatment success. [Journal Article]
- SMSleep Med 2019; 54:187-194
- CONCLUSIONS: Only variables related to sleep position proved to be independent predictors of success with MAD therapy. The results could be explained by the MAD counteracting the mandible from moving backwards when sleeping supine.