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2,189 results
  • Plasmapheresis for the Treatment of Crescentic Postinfectious Glomerulonephritis: A Case Report. [Case Reports]
    Blood Purif 2019; :1-4Gökalp C, Turkoglu RG, … Ustundag S
  • Postinfectious glomerulonephritis (PIGN) is an immune-mediated glomerulonephritis caused by bacterial infections. Treatment of PIGN includes appropriate treatment of underlying infection and supportive treatment of the nephritic syndrome. Immunosuppressive drugs may be used to treat PIGN who have a renal failure with or without crescents and suggested only to the patients who does not have an act…
  • Investigation of epigenetics in kidney cell biology. [Journal Article]
    Methods Cell Biol 2019; 153:255-278Li LX, Agborbesong E, … Li X
  • Epigenetics is the study of heritable changes in DNA or its associated proteins except mutations in gene sequence. Epigenetic regulation plays fundamental roles in the processes of kidney cell biology through the action of DNA methylation, chromatin modifications via epigenetic regulators and interaction via transcription factors, and noncoding RNA species. Kidney diseases, including acute kidney…
  • Nephroprotective effects of red beetroot-based beverages against gentamicin-induced renal stress. [Journal Article]
    J Food Biochem 2019; 43(7):e12873Iahtisham-Ul-Haq , Butt MS, … Shahid M
  • The objective of this study was to assess the nephroprotective effects of red beetroot-based beverages to ameliorate gentamicin-induced renal stress. For the purpose, normal and nephrotoxicity-induced Sprague Dawley rats were pretreated with beetroot-based beverages (8 ml/kg per day) for 8 weeks. In nephrotoxicity-induced rats, renal stress was induced by administration of gentamicin at 85 mg/kg …
  • Vitamin D supplementation for women during pregnancy. [Review]
    Cochrane Database Syst Rev 2019; 7:CD008873Palacios C, Kostiuk LK, Peña-Rosas JP
  • CONCLUSIONS: We included 30 trials (7033 women) across three separate comparisons. Our GRADE assessments ranged from moderate to very low, with downgrading decisions based on limitations in study design, imprecision and indirectness.Supplementing pregnant women with vitamin D alone probably reduces the risk of pre-eclampsia, gestational diabetes, low birthweight and may reduce the risk of severe postpartum haemorrhage. It may make little or no difference in the risk of having a preterm birth < 37 weeks' gestation. Supplementing pregnant women with vitamin D and calcium probably reduces the risk of pre-eclampsia but may increase the risk of preterm births < 37 weeks (these findings warrant further research). Supplementing pregnant women with vitamin D and other nutrients may make little or no difference in the risk of preterm birth < 37 weeks' gestation or low birthweight (less than 2500 g). Additional rigorous high quality and larger randomised trials are required to evaluate the effects of vitamin D supplementation in pregnancy, particularly in relation to the risk of maternal adverse events.
  • [Postinfectious rapidly progressive glomerulonephritis in a pediatric patient]. [Journal Article]
    Arch Argent Pediatr 2019; 117(4):e363-e367Serrano Viñuales I, Ruiz Del Olmo Izuzquiza I, … Justa Roldán ML
  • Postinfectious glomerulonephritis is rarely presented as rapidly progressive glomerulonephritis in children; the prevalence is approximately 1-3 %. Most children have acute onset of renal failure; initial treatment involves corticosteroids and immunosuppressive therapy. Early diagnosis improves prognosis. In recent years, an entity known as "C3 glomerulopathies" has been described, presenting cha…
  • Genetic spectrum of renal disease for 1001 Chinese children based on a multicenter registration system. [Journal Article]
    Clin Genet 2019Rao J, Liu X, … for “Internet Plus” Nephrology Alliance of National Center for Children's Care
  • To explore the approaches and diagnostic yield of genetic testing for renal disease in children, we describe the genotype and phenotype of the national cohort of children with renal disease from 13 different regions of China recruited from 2014 to 2018 by building up the multicenter registration system (Chinese Children Genetic Kidney Disease Database, CCGKDD). Genetic diagnosis was confirmed in …
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