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2,254 results
  • Uncommon Presentations of Multiple Myeloma. [Review]
    Cureus. 2020 Jun 01; 12(6):e8400.Tathineni P, Cancarevic I, Malik BH
  • Multiple myeloma is a rare malignancy that exhibits a wide range of possible clinical presentations. In recent years, with the advent of stem cell transplantation, the prognosis of patients with multiple myeloma has been increasing. We searched the literature for reports of atypical myeloma presentations to aid clinicians in formulating differential diagnoses and to increase the number of cases d…
  • [Mesalazine renal lithiasis.] [Journal Article]
    Arch Esp Urol. 2020 Jul; 73(6):561-564.Vílchez A, Orts JA, … Benavent G
  • Mesalazine (5-aminosalicylic acid, 5-ASA),is an anti-inflammatory drug well-established as first-line treatment in the management of inflammatory bowel disease. Nephritic colic has been described as an uncommonside effect, but very few mesalazine nephrolithiasis have been published in the literature, probably due to its underdiagnosis for not using appropriate methodology for calculi analysis. We…
  • The treatment and follow-up of "recurrence" with discharged COVID-19 patients: Data from Guizhou, China. [Journal Article]
    Environ Microbiol. 2020 Jul 06 [Online ahead of print]Tian M, Long Y, … Zha Y
  • We reported 20 cases of discharged COVID-19 patients whose RT-PCR test results showed "re-positive". After finding "re-positive ", these patients were admitted to hospital for the second time and were followed up until the end of May 2020. Methods: Record detailed treatment and follow-up process, and collect relevant data. The possible causes and potential clinical significance of this phenomeno…
  • Obesity is associated with severe clinical course in children with Henoch-Schonlein purpura. [Journal Article]
    Pediatr Nephrol. 2020 Jun 29 [Online ahead of print]Dundar HA, Pektanc M, … Kavukcu S
  • CONCLUSIONS: Obese children with HSP had higher erythrocyte sedimentation rate, hypertension, and severe renal involvement; showed delayed improvement of skin, joint, and kidney findings; and need more immunosuppressive medications and a longer period of steroid treatment. These findings may be associated with the effect of adipose tissue on inflammation.
  • Choroidal Thickness and microRNA146 in Lupus Nephritis Patients. [Journal Article]
    Clin Ophthalmol. 2020; 14:1503-1510.Hassan Salah S, Makled HS, … Koptan D
  • CONCLUSIONS: The choroidal thickness was significantly thicker among the nephritic lupus patients as compared to the non-nephritic subgroup. Both SLE patients' subgroups are thinner than normal control. Subfoveal choroidal thickening can be considered a biomarker in nephritic lupus especially in conjunction with an increase in miRNA146a. All SLE patients are at risk of small Drusen-like deposits.
  • Rapidly progressive glomerulonephritis and acute kidney injury associated with cocaine use - Case report. [Journal Article]
    J Bras Nefrol. 2020 Jun 22 [Online ahead of print]Pimentel PVS, Freitas HC, … Daher EF
  • A wide spectrum of renal complications can occur with acute and chronic use of cocaine. Most cases are related to rhabdomyolysis, but other mechanisms are malignant hypertension, renal ischemia, and rapidly progressive glomerulonephritis (RPGN) associated-ANCA vasculitis. In recent years, the use of cocaine adulterated with levamisole has been associated with ANCA vasculitis and pauci-immune RPGN…
  • StatPearls: Rapidly Progressive Glomerulonephritis [BOOK]
    . StatPearls Publishing: Treasure Island (FL) Naik Ruchi H. RH Vanderbilt University Medical Center Shawar Saed H. SH Vanderbilt University Medical Center BOOK
  • Rapidly progressive glomerulonephritis (RPGN) is a clinical and pathological syndrome; a term used to describe the following: 1. Rapid loss of renal function over a very short period (days to weeks). 2. Nephritic urine analysis: proteinuria, micro or macroscopic hematuria, dysmorphic red blood cells (RBC), RBC cast. 3. Histopathological characteristic on renal biopsy finding; cellular crescent fo…
  • An update to the pathogenesis for monoclonal gammopathy of renal significance. [Review]
    Crit Rev Oncol Hematol. 2020 May; 149:102926.Zuo C, Zhu Y, Xu G
  • Monoclonal gammopathy of renal significance (MGRS) is characterized by the nephrotoxic monoclonal immunoglobulin (MIg) secreted by an otherwise asymptomatic or indolent B-cell or plasma cell clone, without hematologic criteria for treatment. The spectrum of MGRS-associated disorders is wide, including non-organized deposits or inclusions such as C3 glomerulopathy with monoclonal glomerulopathy (M…
  • Evaluation of the children with C3 glomerulopathy. [Journal Article]
    Saudi J Kidney Dis Transpl. 2020 Jan-Feb; 31(1):79-89.Pinarbasi AS, Dursun I, … Dusunsel R
  • C3 glomerulopathy (C3G) is a clinical spectrum that presents with a variety of symptoms, ranging from a mild disease with asymptomatic microhematuria and/or proteinuria to severe disease with nephritic or nephrotic syndrome and renal impairment. Herein, we aim to document the clinical and laboratory findings, response to immunosuppressive and supportive treatment and prognosis of the children wit…
  • An update to the pathogenesis for monoclonal gammopathy of renal significance. [Review]
    Ann Hematol. 2020 Apr; 99(4):703-714.Zuo C, Zhu Y, Xu G
  • Monoclonal gammopathy of renal significance (MGRS) is characterized by the nephrotoxic monoclonal immunoglobulin secreted by an otherwise asymptomatic or indolent B cell or plasma cell clone, without hematologic criteria for treatment. These MGRS-associated diseases can involve one or more renal compartments, including glomeruli, tubules, and vessels. Hydrophobic residue replacement, N-glycosylat…
  • Epidemiology of 10-year paediatric renal biopsies in the region of southern Croatia. [Journal Article]
    BMC Nephrol. 2020 Feb 26; 21(1):65.Arapović A, Vukojević K, … Saraga M
  • CONCLUSIONS: Changes in epidemiology of renal diseases in children between the analyzed periods showed an increasing trend of IgAN, MCD, HSPN, AS and FSGS, while mesangioproliferative glomerulonephritis (MesPGN) and endoproliferative glomerulonephritis (EDGN) showed a decreasing trend that can be explained with the new pathohistological classification.
  • Anti-Factor B Antibodies and Acute Postinfectious GN in Children. [Journal Article]
    J Am Soc Nephrol. 2020 Apr; 31(4):829-840.Chauvet S, Berthaud R, … Frémeaux-Bacchi V
  • CONCLUSIONS: These findings elucidate the pathophysiologic mechanisms underlying acute postinfectious GN by identifying anti-factor B autoantibodies as contributing factors in alternative complement pathway activation. At onset of a nephritic syndrome with low C3 level, screening for anti-factor B antibodies might help guide indications for kidney biopsy to avoid misdiagnosed chronic glomerulopathy, such as C3 glomerulopathy, and to help determine therapy.
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