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29,760 results
  • Cortical quantitative MRI parameters are related to the cognitive status in patients with relapsing-remitting multiple sclerosis. [Journal Article]
    Eur Radiol 2019van Wijnen A, Petrov F, … Gracien RM
  • CONCLUSIONS: Microstructural changes are distributed heterogeneously across the cortex in RRMS/CIS. QMRI has the potential to provide surrogate parameters for the assessment of cognitive impairment in these patients for clinical studies. The characteristics of cognitive impairment in RRMS might depend on the distribution of cortical changes.• The goal of the presented study was to investigate cortical changes in RRMS/CIS and their relation to the cognitive status, using multiparametric quantitative MRI. • Cortical T2, T2*, and PD increases observed in patients appeared heterogeneous across the cortex and their distribution differed between the parameters. • Vertex-wise correlation of T2 with neuropsychological scores revealed specific patterns of cortical changes being related to distinct cognitive deficits.
  • Fatal Encephalopathy with Wild-Type JC Virus and Ruxolitinib Therapy. [Journal Article]
    Ann Neurol 2019Reoma LB, Trindade CJ, … Nath A
  • CONCLUSIONS: This expands the spectrum of identified JCV diseases associated with broad-spectrum immunosuppression, including JAK-STAT inhibitors, and sheds light on an additional neurotropic virus strain of the archetype variety. This article is protected by copyright. All rights reserved.
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