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2,552 results
  • Sex differences in fatigability and recovery relative to the intensity-duration relationship. [Journal Article]
    J Physiol 2019Ansdell P, Brownstein CG, … Goodall S
  • CONCLUSIONS: Females demonstrate greater fatigue-resistance than males during contractions at intensities relative to maximum force. However, previous studies haven't accounted for the influence of metabolic thresholds on fatigability. This study is the first to test whether sex differences in fatigability exist when exercise intensity is normalised relative to a metabolic threshold: the critical intensity derived from assessment of the intensity-duration relationship during intermittent, isometric knee extensor contractions. We show that critical intensity in females occured at a higher percentage of maximum force compared to males. Furthermore, females demonstrated greater fatigue resistance at exercise intensities above and below this metabolic threshold. Our data suggests that the sex difference was mediated by lesser deoxygenation of the knee-extensors during exercise. These data highlight the importance of accounting for metabolic thresholds when comparing fatigability between sexes, whilst emphasising the notion that male data is not generalisable to female populations.
  • Responsive neurostimulation targeting anterior thalamic nucleus in generalized epilepsy. [Journal Article]
    Ann Clin Transl Neurol 2019Herlopian A, Cash SS, … Cole AJ
  • Responsive neurostimulation (RNS) has emerged as an adjunctive treatment modality for patients with intractable focal epilepsy who are not surgical candidates or have more than one ictal onset focus. We report a 34-year-old patient with intractable, childhood-onset, genetic generalized epilepsy (GGE) with tonic, atonic, myoclonic and absence seizures treated with RNS. Strip electrodes over the ri…
  • Gastric Electric Stimulation for Refractory Gastroparesis. [Journal Article]
    J Clin Outcomes Manag 2019; 26(1):27-38Zoll B, Jehangir A, … Parkman HP
  • CONCLUSIONS: GES may be considered among the therapies available for treating patients with refractory symptoms of gastroparesis. More studies, specifically those comparing GES, pyloromyotomy, GES combined with pyloromyotomy, and placebo, are needed to help guide therapy selection for refractory gastroparesis.
  • Heart Rate Variability and Vagus Nerve Stimulation in Epilepsy Patients. [Journal Article]
    Transl Neurosci 2019; 10:223-232Constantinescu V, Matei D, … Cuciureanu DI
  • CONCLUSIONS: VNS therapy in epilepsy patients seems not to disrupt the cardiac autonomic function. HRV represents a useful tool in evaluating autonomic activity. More extensive studies are needed to further explore cardiac autonomic response after neurostimulation.
  • Management of Meibomian Gland Dysfunction: A Review. [Review]
    Surv Ophthalmol 2019Sabeti S, Kheirkhah A, … Dana R
  • Meibomian gland dysfunction (MGD) is the leading cause of evaporative dry eye disease and is one of the most common conditions encountered by eye care providers. MGD is characterized by obstruction of the meibomian gland terminal ducts and/or changes in their glandular secretion, resulting in changes in tear film stability, inflammation, and symptoms of irritation. There is no gold standard treat…
  • Bifid facial nerve with dual origin identified during resection of vestibular schwannoma. [Journal Article]
    World Neurosurg 2019Harley B, Rosenfeld JV, Cousins V
  • Facial nerve identification and preservation is a critical step in the resection of vestibular schwannoma. The use of intraoperative neurostimulation to positively identify the facial nerve along its entire course is essential to prevent injury. This is the first reported case of a bifid facial nerve with a dual origin at the brainstem which we observed during resection of vestibular schwannoma v…
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