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(neurulation)
1,514 results
  • Junctional neural tube defect in a newborn: report of a fourth case. [Journal Article]
  • CNChilds Nerv Syst 2017 Feb 28
  • Schmidt C, Voin V, … Oakes WJ
  • CONCLUSIONS: Characterized by an error in junctional neurulation in which the primary and secondary NT fail to integrate appropriately, JNTD has been recently classified. We believe the current patient to represent only the fourth reported case of JNTD in the literature.
  • New classification of spinal lipomas based on embryonic stage. [Journal Article]
  • JNJ Neurosurg Pediatr 2017; 19(4):428-439
  • Morota N, Ihara S, Ogiwara H
  • CONCLUSIONS: Secondary neurulation of the spinal cord gives rise to the conus medullaris and filum terminale, which are often involved in spinal lipomas. Formation of spinal lipomas seems to be a continuous process overlapping primary and secondary neurulation in some cases. Association with other anomalies was higher in Type 2-4 spinal lipomas, which included failed secondary neurulation, than in Type 1 lipomas, with failed primary neurulation. On the other hand, radical resection was indicated for Type 1, but not for Type 2, spinal lipomas. The new classification of spinal lipomas based on embryonic stage has the potential for clinical use and agrees well with both clinical and surgical findings. The classification proposed here is still preliminary. Further studies and verification are necessary to establish its clinical utility.
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